مجله علمی پزشکی جندی شاپور
سال یازدهم شماره 3 (پیاپی 78، امرداد و شهریور 1391)

Postmenopausal vaginal bleeding (PMB) is a common and important clinical problem. PMB is caused by endometrial cancer in about 10% of patients. Most reports indicate that endometrial atrophy is the most common cause of PMB. Most of them for more evaluation are admitted for dilatation and curettage (D&C). The purpose of this study is to find in which patients, transvaginal ultrasonography (TVS) can replace with D&C? Subjects and From April, 2008, through June, 2009, 98 women with PMB underwent TVS and histopathologic evaluation of the endometrium after D&C or after hysterectomy. Normal appearance at transvaginal sonography was defined as a thin (≤ 5 mm) and diffuse smooth with smoothly marginated and homogeneously echogenic endometrium. However a suspicious appearance was defined as either irregular thickening of the endometrium or an inhomogeneous endoluminal mass or pedunculated endoluminal mass or any endometrial thickness above 5 mm. At histologic examination: of 98 women, 44 (45%) had an atrophic endometrium, 11 (11%) had carcinoma, 10 (10%) had hyperplasia, 28 (29%) had polyps and 5 (5%) were others (ovarian tumor, leiomyosarcoma and multiple or giant leiomyoma) For carcinoma, the sensitivity of TVS was 100 %, specificity was 41.38 %, PPV was 17.4 %, and NPV was 100 %. In addition, the specificity of TVS for atrophic endometrium was 100 %. TVS in patients with PMB is an excellent tool for the determination of whether further investigation with curettage or some form of endometrial biopsy is necessary and sensibly decreases the number of invasive methods. TVS also improves clinical decision- making, and the clinician’s diagnostic certainty

Cellulitis is an acute infection of cutaneous and subcutaneous tissue. Inaccurate treatment of cellulitis can cause important complications like abscess, myositis, osteomyelitis, bacteremia, septicemia, endocarditis, meningitis, and other complications and can lead to death. The aim of this study was to assess the epidemiology of cellulitis that result in complication among in-patients in infectious diseases ward. Subjects and The population of the study included all patients admitted with final diagnosis of cellulitis in the infectious ward of Ahvaz Razi hospital during 2001-2003. Regarding variables under study (age, sex, occupation and underlying diseases), the relation between complications caused in relation to each of the complications and these variables were assessed. Data were analyzed by SPSS-15 and using descriptive and analytical statistical methods and chi-squared test with P

Anxiety, depression, nausea and vomiting most common side- effects from chemotherapy. This study evaluates the effects of massage therapy on this side-effects of chemotherapy. Subjects and This study was a clinical trial that 34 patients with breast cancer were studied. After exposure of patients to ensure some degree of depression and anxiety and having nausea and vomiting during previous chemotherapy, patients randomly divided into intervention and control groups. Intervention patients had three sessions back massage addition to usual care received. Control group only received usual care. In the first 24 hours after each massage questionnaire were completed. Results shown that anxiety days of 2-4 with (P=0.0009, P=0.04, P=0.03) and depression with(p=0.03, p=0.03, p=0.01) between two groups statistically significant differences but nausea with (P=0.29, P=0.07, P=0.51) and vomiting with(p=0.53, p=0.84, p=0.8) statistically significant differences not seen. According to research findings that show the effects of massage therapy on reduction anxiety and depression, is recommended as a method of massage available, convenient and cost-effective to improve anxiety and depression. massage reduced nausea and vomiting but not be too significant and further studies will recommended.

Dysphagia refers to any disturbance in movement of food bolus from mouth to stomach that is due to neurological motor disorder of swallowing processes. Depending on many factors, prevalence of dysphagia is reported differently. Since, a speech and language pathologist is an active member of the medical team assessing and treating patients with dysphagia, having basic information about prevalence and etiology of dysphagia seems necessary for short and long-term planning of rehabilitation programs. Subjects & In this retrospective descriptive-analytic study, 1860 medical profiles of Hospitalized Patients of Educational Hospitals of Ahvaz-city were randomly selected. By use of NDPCS checklist, data regarding existence and nonexistence of dysphagia, etiology of dysphagia, prevalence of dysphagia in different ages and sexes, accompanying speech disorders, and prevalence of dysphagia in different wards of the studied hospitals were recorded and entered into SPSS software for analysis. Among 1860 viewed medical profiles, 4.2% of patients had dysphagia (4% male, 4.5% female). No significant difference was observed between male and female regarding prevalence of dysphagia (p>0.05). Neurologic diseases were the most frequent causes of dysphagia. Regarding prevalence of dysphagia in different ages, males having between 0–10 years of age had the highest dysphagia rate respectively. The highest and lowest dysphagia rate was observed in Neurology ward and Internal Medicine ward of the studied hospitals. Speech therapists are suggested to pay more attention to age, common etiology (infections), and hospital wards with higher dysphagia rate and it is suggested to use early interventions for dysphagia.

Backgrand: pain has been identified by rheumatoid arthritis patients as a distressing symptom that interfere their ability to enjoy life and to take care of themselves.complementary medicine is applied in limited study.The purpose of the syudy was to effect of acupressure intensity pain in rheumatoid arthritis patients. the study was a clinical trial, data were collected in a clinic of rehumatoloy golestan hospital in ahwaz, physician surgery and patient home.amog these patient, 60 were selected fulfilling criteria and randomaly divided to 2 acupressure and control groups. The main outcomes measured were the demographic form and VAS scale that were collected at first and last intervention sessions. Acupressure accomplised with direct finger pressure at 1 minute in Hegu, Quchi, Zusanli and Taichong within 12 session, control group no received complementary treatment in this time. Then data analysis with SPSS version 17 and paired t-test test. The result of study indicated that between averages of pain intensity in acupressure and control groups pretreatment and after was no significant difference (p=0.813). However in study indicated that between averages of pain intensity in acupressure and control groups was no significant difference but in context of acupressure more researchs have required.

Sensorimotor deficits in chronic nonspecific neck pain may be altered cervical afferent input. Altered sensory input the cervical spine structur, mediated via the direct neurophysiological connections to vestibular and visual system has the potential to disturb postural control. This study compare postural performance between subjects with nonspecific chronic neck pain and a matched control group without CNP. In this case-control study, postural stability was measured by force plate in (24) nonspecific chronic neck pain &(24) matched healthy subjects. Each case performed double limb &single limb standing with 2 level of difficulty (rigid-foam surface). Measured parameter were mean velocity, standard deviation velocity in the media-lateral and antero-posterior direction. Data were analyzed by 2-way repeated measurement ANOVA. Finding shows that subjects with non-specific CNP had significant increase in standard deviations for velocity in the antero-posterior and media-lateral direction in single limb stance. In double limb stance no statistically significant differences were found between groups. dissimilarity in postural performance chronic nonspecific neck patient are reflection of different degrees of disturbances of the proprioceptive input to central nervous system and/or of the central processing of such input. It is suggested that consider treatment method for address neck position and movement sense and balance training

Hypericin is a naphtodianthrone with multiple pharmacologic actions. Hypericum triquetrifolium Turra grows in different part of Iran. The aim of the present study was to isolate and determine the quantity of hypericins in different parts (leaf, flower and stem) of this plant grown in Khozestan province. Matrials & Different parts of Hypericum triquetrifolium Turra (leaf, flower and stem) were collected and extracted with methanol 50% using soxhlet apparatus. Hypericin was determined using UV/Visible spectrophotometer at 590 nm. The percents of hypericin in leaves, flowers and stems were 310, 210 and 150 mg/100g, respectively. Leaves and flowers of Hypericum triquetrifolium Turra have considerable amounts of hypericin

Thalassemia is the most common monogenic disorder in human. The major type has sever clinical symptoms with craniofacial defects, that produce estetic problem in patients. Orthodontic treatment and surgical reconstruction in these patients have had good estethic results and therefore satisfying pschycosocial effects. Reserches have shown an increase at the level of life guality corresponding to health improvement in thalassemic patients. In Iran prevalence of thalassemia is relatively high (% 5 - %10) and kuzestan province is ranked as the second province involved in Iran More knowledge and information is necessary for better treatment of skeletal problem of thalassemia. Therfore this study was performed in orther to get more information knowledge about talassemia. Subjectis and This descriptive and analytic study was performed on 48 beta thalassemia major paitients and 48 normal samplls. They were divided in two groups (24 persons) based on their genders. Including criteria for samples were: being more than 15 years orthodontic and orthopedic treatment, Cl I profile, normal facial height, Cl I molar relation ship, normal overbite and over jet, presence of all permanent teefh (except third molar) in mouth dentol arch combination cophalometric analysis was used for evaluation of cephalometric analysis was used for evaluation of cephalograns. The results were analyzed using descriptive statistical and (P)

Field goal: Improving the economic status and health in the elderly population are growing. But we consider that only increased longevity is not symptoms of development, quality of life is more important. Quality of life of elderly people is influenced by several factors, one of the most important factors is support social. This survey was done among 380 elderly men and women have been living in the city of Kerman. The research tool was a questionnaire with interview; questionnaire and the SF36 was used for assessing the quality of life and for measuring social support; a questionnaire was used. The most important supporters were in the first degree was wife/husband and then son and in third grade daughter. Mean score of physical quality of life was more than average mental health score. The results showed that emotional support, financial services, advisory and information, and age relationship with both components of quality of life According to the findings by increasing the types of social support, especially emotional support can be a great help to improve the quality of life for seniors.

Introduction & Sickle cell anemia is a genetic disorder and hemolytic anemia. This anemia can damage organs. HbS hemoglobin and deoxygenating in peripheral tissues can be death in the patients. Exercise is a risk factor. But it remains unclear in patients with HbS display any disturbance during anaerobic or aerobic exercise in sickle cell trait. This study aim is determination of the effect of aerobic exercise on 0 saturation in children with sickle cell trait. Eighty two (82) healthy and trait children in two groups: case and control (age 6-18) participated in this study. Anthropometrics profile and hemoglobin concentration were measured. HbS hemoglobin recognized with HPLC. All children did exercise on cycle ergometer 2min exercise and 3min rest. Before and fter exercise heart rate and 0 saturation assessd by pulseoximetry. there was no significant difference between two groups for 0 saturation before and after exercise. This parameter remained normal limited in children with sickle cell trait. it seems aerobic exercise is safe for these children.

Increasing evidence on human and animal studies have suggested that exercise has benefits on overall health. It has been shown that exercise stimulated endogenous antioxidant enzymes and reduced oxidative damage markers. Morphine (M) is widely used for relief of severe pain. The mechanism by which M –induced toxicity is due to generation of reactive toxic intermediates. To evaluated the effect of exercise on M produced toxicity in rat liver and kidney Subjects and M was given ip two times per day for 5 consecutive days. 1st day 5mg/kg,2nd day10 mg/kg, 3rd day 20mg/kg, 4th day 40mg/kg and 5th 50mg/kg. Control animals received vehicle only. Treated rats were divided in 4 groups. One group of M and vehicle treated rats were participated in the treadmill exercise sessions (1 h at speed 17 m/min) for 10 consecutive days. and two other group did not participated in the exercise.24 h later, rats were killed with overdose of sodium pentobarbital. Blood was collected for determination of ALT, AST, ALP, BUN and creatinine. Liver and kidney tissues were removed, fixed and processed for light microscopy. 10 animals were used for each group. Biochemical and histopathological observations indicated that M produced injury in the liver, and kidney. Exercise reduced M-induced toxicity (p

Pneumatosis intestinalis is usually benign condition which may affects any segment of gastrointestinal tract from stomach to rectum. It is also called pneumatosis cystoides intestinalis (PCI). It is best classified in to (A) a primary form and (B) a secondary form. Air cysts are found mostly in subserosa of large bowel. The aim of this study is to present 72-year–old heavy smoker man that refers to emergency department with abdominal pain, nausea, vomiting and decreased appetite for three days duration. With impression of peritonitis due to hallow viscus perforation, patient underwent laparotomy. Abdomen was completely clean without any puss or fluid. There were multiple gas-containing cysts over the antimesentric colonic wall of the transverse and sigmoid colon. We terminated the operation without any intervention. The patient became symptom free post operatively and discharged from hospital with good condition.