نشریه ارمغان دانش
سال نوزدهم شماره 5 (پیاپی 88، امرداد 1393)

Exercisecauses to enhance synaptic plasticity and neuroprotective effects in the adult brain. However، it remains unknown that how plasticity molecules were changed following types of training. The purpose of this study was to determine the effect of eight weeks resistance training on protein levels of Brain Derived NeurotrophicFactor (BDNF) and receptor of TrkB، in the hippocampus of adult male rats. This experimental study was conducted with the animal model. so 12 adult male vistar rats، 8 weeks of age and with mean body weight of 200-225 gr were selected as subjects. The animals randomly divided into 2 groups of control (n=6) and train (n=6). Resistance training included weight lifting up on a vertical ladder. After 24 hours of the last session of training، the animals were sacrificed and the hippocampus of both side of hemisphere removed. Changes in protein levels were determined with ELISA technique. The data were analyzed with using independent T test. There was a significant difference (p≤0. 05) between train and control groups In protein level of variablesstatically.; and resistance training increased protein levels of BDNF and TrkB in the hippocampus of rats. Resistance training is beneficial for promoting hippocampal plasticity associated with BDNF signaling and consequently functional and cognitive benefits.

waves cause hormonal disorders، whereas garlic is known as reducing risk factors associated with various diseases. The aim of this study was to investigate the protective effects of garlic against a hormonal disorder caused by the waves. In the present experimental study، sixty rats were divided into 5male and 5female groups: control، sham (under exposed)، experimental1 (garlic extract)، and experimental2 and3 (both extract and microwaves). After a month، the rats were weighed، their blood samples were collected and concentration of estrogen، progesterone and testosterone were measured. Results were analyzed by SPSS، ANOVA and Tukey tests. In males، the mean weight were reduced in the control group than in the sham group، but increased in the experimental group than the control group 3. Testosterone concentrations of experimental groups 2 and 3 were decreased but in all groups showed a decline in estrogen. Progesterone also increased in all groups. Weight loss due to radiation observed in males were compensated with compounds such as thiamine، vitamin A contained in garlic allicin. Microwaves and garlic extract have effects on testes which reflected in the number of Leydig cells and serum testosterone and estrogen concentration. Progesterone increased as a result of waves on the hypothalamus and the stimulatory effect of garlic on the secretion of ovarian hormones. Thus، Garlic cannot overcome all detrimental effects of waves.

Refractive errors are the most common reasons for patients'' referring ophthalmology clinics. The purpose of this study was to determine prevalence and characteristics of refractive errors in the patients with primary hypertension in Shahrekord. In this descriptive، analytical، cross-sectional study 217 patients with primary hypertension were examined for refractive errors by an ophthalmologist. Systolic pressure of > 140 mmHg and diastolic pressure of > 90 mmHg were considered as increase in blood pressure and refraction equal to ± 0. 5 as refractive error. The data were analyzed by chi-square and t test. The prevalence of refractive errors in hypertension patients was 72. 35%. 36. 4% of the patients had myopia، 36. 9% had hyperopia، and 26. 7% had emmetropia. No significant difference in hypertension-derived refractive errors was observed among myopic، hyperopic، and emmetropic patients (p < 0. 05). The risk of developing hyperopioa in primary hypertension patients is higher than that of developing myopia and emmetropia. In addition، there is no association between the rate of mean blood pressure and hyperopia.

Urinary tract infection is the most common childhood infections after upper respiratory tract infection. Early diagnosis، proper treatment and appropriate patient follow-up can lead to a significant reduction in symptoms. The purpose of this study was to determine the antimicrobial resistance of urinary tract infection in children under 14 years admitted to the pediatric clinic of Imam Sajjad (AS) Yasooj. In this cross-sectional study antibiotic sensitivity of 145 positive urine cultures were evaluated by disc diffusion method. Urine specimens were collected by suprapubic aspiration and catheterization urethral in children without urinary incontinence and Mid Stream Clean-Catch method. Data were analyzed by chi square test. Among the patients were studied، 60. 68% female and 39. 31% were male. The most common cause of urinary tract infections in children، Escherichia coli (72. 41%)، followed by Klebsiella (34/10. 34%). Antibiotic resistance patterns including ampicillin (85. 51%)، amoxicillin (/83. 44%)، cephalexin (69. 65%)، cephalothin (62. 06%)، cotrimoxazole (37. 61%)، nalidixic acid (44. 82%)، cefixime (24. 37%)، nitrofurantoin (36. 55%)، gentamicin (35. 17%)، ceftriaxone (28. 27%)، ciprofloxacin (26. 89%)، amikacin (25. 51%)، and cefotaxime (24. 82%) were respectively. Antibiotic resistance in urinary tract infections of children in Yasuj in 2012 was higher than previous years except for amikacin، But it was a remarkable increase in ciprofloxacin and co-trimoxazole. The use of nitrofurantoin، cefotaxime، third generation cephalosporins and aminoglycosides is recommended for empirical treatment.

Radiology personnel are working in terms of performance and safety in one of the most important functions is to increase the quality and quantity. This study aimed to evaluate the radiological standards in 92 YASUJ Beheshti Hospital. This research is a descriptive - analytical study is based on 118 sampling graph sampling and the list ranking list and with full knowledge of standard radiological evaluation was performed two times، then the software were analyzed using SPSS software. The study was conducted on 118 imaging varies in different patients 56. 8% were male and 43. 2% were female. In this study، the radiology staff and students of YASUJ Shahid Beheshti Hospital (RAH) in the selection cassette 87. 3%; choose the positioning of the patients76. 3%; selected member position87. 3%; the choice of the central ray 83. 9%; choose the distance between the tube to the patient68. 6%; has been operated in accordance with the standards. In addition، among all the factors and variables، between view with cassette - view with SID-sex with position patients - grid with central ray- grid with Source Image to Distance - Request with positioning the patient and between density with patient position & member position Significant relationship was observed. Research findings indicate that staff and students in good in terms of performance (x> 50%) but in terms of protecting the poor and weak (x <50%) are located. It is recommended to promote their conservation، education and continuous monitoring should be performed periodically.

There is no general consensus on the minimum dose of propofol for maintenance of anesthesia. The purpose of this study was to determine the effect (s) of two different doses of propofol on cardiovascular responses in patients undergoing Septoplasty surgery. In the present clinical-trial study، fifty-eight patients (15 to 55 years) candidate for nasal Septoplasty were randomly divided into two groups of A (propofol infusion dose 50µg/kg/min) and B (propofol infusion dose 100µg/kg/min). After induction of anesthesia and intubation، propofol infusion was started with two different doses. Systolic، diastolic and mean arterial blood pressures were measured at 0، 2، 5، 10، 15، 20، 30، 45 and 60 minutes after initiation of infusion. The depth of anesthesia during the surgery and wake-up time was evaluated. The data were analyzed by independent sample t-test، Mann-Whitney U test، repeated measure and Freidman. Wake up time in group A and B was (28. 71±3. 19) and (31. 00±5. 29) min respectively which no significant differences were observed between the two groups. Changes in heart rate and systolic blood pressure، diastolic and mean arterial at different minutes in each group compared with the other two groups showed no significant difference (p> 0. 05). Increasing dose of propofol from 50µ/kg/min to 100µ/kg/min does not affect the depth of anesthesia، cardiovascular responses and wake up time، so a lower dose of propofol infusions is recommended during general anesthesia.

Recurrent pregnancy loss (RPL) refers to the occurrence of two or more consecutive losses of clinically recognized pregnancies prior to the 20th week of gestation. The aim of this study was to investigate the hypothesis that recurrent pregnancy loss (RPL) is associated with a common insertion-deletion polymorphism in the angiotensin-converting enzyme gene.. The present paper intended to study the ACE deletion (D) /insertion (I) polymorphism in women with recurrent abortion. One hundred patients with recurrent abortions (at least two) as cases and one hundred healthy female with two or more normal term deliveries and without a history of abortion selected as controls. Genomic DNA was isolated from peripheral blood leukocytes and the ACE insertion/deletion (I/D) polymorphism in intron 16 was performed by polymerase chain reaction (PCR). For the statistical analysis، SPSS software version18 was used and Chi-square tests were calculated. Seven patients، (7 %)، and non from the control group، were homozygote (I/I) for ACE polymorphism (OR=22. 82; 95% CI=1. 26-412. 69; p=0. 034)، depicting no significant associations between ACE D allele or DD genotype and RPL. The present study showed no significant associations between ACE D allele or DD genotype and RPL.

Diabetes is a metabolic disease characterized by the chronic hyperglycemia and impaired metabolism of carbohydrates، Lipids and proteins. The aim of the present study was to investigate the effect (s) of eight weeks of resistance training on liver inflammatory indices (circulating levels of liver enzymes، Alanine aminotransferase (ALT)، Gamma-glutamyltransferase (GGT)، and Aspartate aminotransferase (AST) in women with type II diabetes disease. In the present study، twenty diabetic women ageds 44 -69 years were randomly assigned into two groups، control and intervention groups respectively. The subjects in the experimental group participated in eight weeks of resistance training، three sessions per week and each session lasting 45 minutes. In order to compare data within groups and the between groups t-test and independent t-test were used respectively. Conducted eight weeks of resistance training resulted in a significant decrease in serum levels of the alanine aminotransferase، aspartate aminotransferase and gamma glutamine transferase of liver، fasting blood glucose، insulin and insulin resistance in the experimental group (p <0. 05). Overall، the eight-week resistance training reduced body fat and weight loss and improved metabolic status indicator of liver inflammation، especially in diabetic patients، but no significant effect on markers of hepatic inflammation was observed. Article keyWords: Resistance Training، Alanine aminotransferase، Gamma-Glutamyltransferase، Aspartate Aminotransferase، Type II Diabetic

Throughout the world، half of the people over 70 years of age suffer from knee osteoarthritis and detection of the factors associated with this disease is important. The present study was conducted to examine the association of knee joint anatomic parameters with osteoarthritis occurrence. In the present observational-comparative study، ninety-four patients with joint osteoarthritis as case group and 106 healthy individuals as control group were enrolled from Orthopedic Clinic of Shahrekord Hospital into the study for comparison. Anatomical parameters such as tibial plateau tilt، Cam effect، and tibial plateau coverage by femoral condyles were calculated by using radiographic findings and compared between two groups. The data were analyzed by SPSS software 16 using chi-square and Pearson correlation Tibial plateau tilt values in patients with osteoarthritis of knee (11. 9±3. 4°) was significantly higher than the control group (10. 2±1. 9 °) (p<0. 001). Cam effect in patients with osteoarthritis (1. 8 ± 0. 1) was higher than control group (1. 7± 0. 1) (p< 0. 001). Index of tibial plateau articular surface occupied by condyles of femur in patients with osteoarthritis were 2/3±9/51% and 1/2±1/50% in the control group respectively (p<001/0). Tibial plateau coverage was identified in patients with osteoarthritis equal to 51. 9 ± 3. 2% and in the control group 50. 1±2. 1%. These parameters were not associated with each other، as well as age and gender (p>0. 05). Anatomic parameters under study could be used to predict osteoarthritis occurrence in healthy individuals.

Multiple Sclerosis (MS) is a chronic disease which disables the nervous system that begins most commonly in young adults and is characterized pathologically by demyelination، and glial scarring. As many psycho– mental problems are caused by MS، the aim of this study was to investigate the effect of the aspects of religious coping on predicting the aspects of quality of life in MS patients. the persent study was a descriptive one. The sample included 43 patients that were selected by the Available sampling in Aliebn Abitaleb Hospital during 2013 in Zahedan، Iran. The variables were measured by the questionnaires of religious coping and quality of life. The data were analyzed by using the correlation and step-wise Regression methods. The results showed that there was a significant relationship between the passive religious coping and the role playing that is caused by emotional problems (from dimensions of quality of life) (P≤. 05). There was a positive and significant relationship between religious activity and benevolently assessment with mental aspect of quality of life. There was a negative significant relationship between passive religious coping and mental aspect of quality of life. Also the regression results showed that in the first step، religious activity Predicted. 07 of changes of psychological quality of life and in the second step، religious activity along with passive religious coping Predicted. 20 of changes of psychological quality of life changes. Therefore، increase of religious and spirituality activities may have significant role in enhance quality of life in MS patients.