نشریه ارمغان دانش
سال بیست و سوم شماره 1 (پیاپی 126، فروردین و اردیبهشت 1397)

Diagnosis and treatment of breast cancer can have adverse effects on the life quality of women. Self-care program seems necessary to improve their quality of life. The aim of this study was to examine the effect of Orem self-care model on the quality of life of women with breast cancer.
In this clinical trial, eighty women with breast cancer who came to the chemotherapy departments of oncology centers in Shiraz participated. The sampling method was as convenience method but selected samples were randomly assigned between the control and intervention groups. Orem's self-care model was taught to patients of intervention group during an eight sessions about forty-five minutes. The QLQ-C30 and QLQ-BR23 questionnaires were used to collect data before intervention and two weeks after the last intervention session. Data were analyzed by SPSS software version 21 through descriptive and inferential statistics, taking into account the significance level of 0.05.
Significant statistical differences were reported in the sub-scales of quality of life namely global health status, physical functioning, emotional functioning, and role functioning, social functioning, body image and future perspective between the two groups after intervention. The median test has shown a significant difference (p 0.05).
Orem's self-care model has been able to improve the quality of life of women with breast cancer by reducing some of the symptoms associated with their illness and treatment.

Carbon tetrachloride, an organic solvent and chemical intermediate used in the industry, can cause numerous side effects including hepatotoxicity. This study was aimed to evaluate the possible hepatoprotective potential of wheat germ oil against carbon tetrachloride-induced hepatic disorders in male mice.
48 male mice were randomly divided into 6 groups of 8 and treated for 4 weeks including control, carbon tetrachloride (1 ml/kg body weight intraperitoneally, 2 times a week),carbon tetrachloride (1 ml/kg body weight intraperitoneally) wheat germ oil (250 mg/kg body weight per day orally), carbon tetrachloride (1 ml/kg) wheat germ oil (500 mg/kg/day orally), wheat germ oil (250 mg/kg body weight per day orally) and wheat germ oil (500 mg/kg body weight per day orally) groups. At the end of the treatment, animal blood was collected to measure liver enzymes including AST, ALT and ALP. Hepatic tissue samples were harvested, fixed in 10% formalin, stained with hematoxylin and eosin and analyzed using optical microscopy. The data were analyzed by one-way ANOVA and Tukey's post hoc test.
In mice receiving carbon tetrachloride combined with wheat germ oil (250 and 500 mg/kg), liver enzymes (ALP, ALT and AST) significantly (p These findings suggest that wheat germ oil can exert hepatoprotection in carbon tetrachloride evoked hepatotoxicities in mice.

Inflammatory bowel disease (IBD), including Crohn's disease and ulcerative colitis, a chronic condition of the intestine with unknown etiology involving different agents immune, genetic and environment. Today, many of herbal and synthetic compounds are being used as anti-inflammatory products around the world. The aim of this study was to investigate the anti-inflammatory effect of aquatic extraction of Teucrium polium L. plant.

In this experimental study, a total of 135 male rats, weighing 200±20 g and 10 to 12 weeks old, were randomly divided into nine equal groups: healthy control group were given normal saline without ulcerative colitis (UC) induction, negative control group which UC was induced by 3% acetic acid with no treatment, basal gel group which were received basal gel via enema after UC induction, two groups as positive controls were taken Asacol (10 mg/kg/day) and Mesalamine (10 mg/kg/day) transrectally and orally, respectively. Also, oral form of aqueous extraction 50 and 100 mg/kg/day and enema form (gel 10% and 20%) of Teucrium polium L. were given. At the end of study, MDA measurement as antioxidant index and histopathological evaluation of colon tissue was performed. The collected data were analysed using one-way ANOVA and Mann–Whitney U test.

the results showed that groups were received enema gels 10% and 20% compared with other groups significantly repaired damaged tissue of colon at the microscopic level and caused reduction in MDA level (p­

Teucrium polium L. has remarkable effects on healing processing of induced colitis in rat. According to anti-inflammation and anti-microbial properties of Teucrium polium L., it can be mentioned that this plant is effective in healing of intestinal ulcers. Also, antioxidant materials of Teucrium polium L. accelerate healing processing.

This study was done to investigate the effect of 17-β estradiol (E2) treatment on the potential of Mesenchymal stem cells (MSC) for modulation of innate immunity responses in the animal model of Rheumatoid arthritis (RA).
After isolation of MSCs, they were co-cultured with 100nµM 17-β estradiol for 24 h. RA was induced by collagen peptide and complete Freund's adjuvant in Wistar rats. One week after immunization, rats were allocated in groups received untreated MSCs (2×106 cells-intraperitoneal), received MSCs pulsed with estradiol and untreated rats. The change in the diameter of wrists and ankles of each rat was recorded every 5 days until 33 days after induction.
The edema and swelling of ankles in the positive control group (5.9 ± 0.6mm) was higher than the treatment groups. foot swelling in RA rats received MSCs treated with 17-β estradiol (1.69±0.45mm) were significantly decreased (P 17-β estradiol-treated MSCs increases regulatory function and inhibitory effect on the inflammatory mediators of spleen innate immune cells in RA model compared to un-treated MSCs.

Nowadays, herbal products often have been used as an alternative or supplement to chemical drugs in treat of diseases with low side effects and cost of treatment. The aim of this study was to survey the effect of aqueous extract of Cinnamon verum on anxiety-like behavior in streptozotocin-induced (STZ) diabetic rats.
This experimental study was carried out on 28 of male Wistar rats with the weight range of 200 ± 30 (g) in which randomly divided into four groups including seven each. The diabetes induced in adult male Wistar rats with an intraperitoneal injection of streptozotocin (50 mg/kg). The experiments were assigned to 3 weeks, rats were treated with extract in dose of 200mg/kg oral in which at the end of experiment animals were transferred to the elevated plus maze (EPM) at adjusted intervals and their anxiety reactions including enterance numbers and time spent in open arm were recorded and investigated in 5 min. The data were analyzed using SPSS software, method of One-way ANOVA and were compared different groups with each other by tukey test. Finally, P≤0/05 was considered statistically significant.
A significant decrease in entrance numbers and time spent in open arm of the elevated plus maze in groups of the treated diabetic rats were seen whereas; there were no significant changes in their anxiety reactions in other groups (non-diabetic)(P≤0.05).
It was thought in this survey, extract of Cinnamon verum with more than 50 different combinations and different effects, can affect nerve disorders of anxiety in adult male rats. But, the findings show that C. verum extract cannot effect on the anxiety-like behavior in adult male rats. However, the anxiety-like behavior increased in induced diabetic adult male rats, significantly. Therefore, it could be suggested that on the one hand probably the concentration of cinnamon used to treat diabetic rats was not sufficient to reduce blood glucose levels and improved effects did not have on the function of neurotransmitter systems for anxiety control. On the other hand, it is likely changes in the activity of neurotransmitter systems in the brain and the occurrence of anxiety behaviors in diabetic rats has been influenced by factors other than glucose levels. As a result, cinnamon extract had no effect on the improvement of anxiety and anxiety – like behaviors due to low blood glucose levels.

The use of Chemotherapy for the treatment of hydatid cysts can be problematic due to different adverse effects. As a result, there is an increasing interest in non-chemical alternatives, such as medicinal plant extracts as new therapeutic tools against hydatid cyst. In the present study, various concentrations of carob extract at different exposure times were evaluated under laboratory conditions for their scolicidal effects on Hydatid Cysts.
Protoscolices were aseptically collected from sheep livers having hydatid cysts and were exposed to three different concentrations of oak and carob extract (10, 25 and 50) mg /ml for 10, 20, 30 and 60 min. Viability of protoscolices was determined by 0.1% eosin staining.
Based on our results, the scolicidal effects of this plant on Hydatid Cysts in all concentrations was significant compared to the control groups (p The results also showed that the extract of this plant produce high scolicidal activity; However, in vivo efficacy of this medicinal plant remains to be studied for treatment of hydatid cysts in humans and herbivorous animals.

Diabetes is the most common metabolic disorder in the world, which can disrupt ovarian function. The present study was designed to examine the effect of Okra powder on ovary histology in high-fat diet fed-streptozotocin (HFD/STZ) induced diabetic female rats.
25 adult Female Wistar rats were divided into 5 equal groups. Group I: (control group): served as helthy rats received normal diets. Group II diabetic(HFD STZ): rats were fed HFD (60% fat 25% carbohydrate 15% protein ) for 4 weeks and then injected with STZ (35 mg/kg body weight). GroupIII(HFD䤶.E): HFD STZ rats were treated with 200 mg/kg powder A. esculentus. Group IV (HFD䤶纙ꊹ): HFD STZ rats were treated with 200 mg/kg metformin. Group V: Normal Diet A. esculentus (200 mg/kg).
After 4 weeks of treatment, animals were euthanized and body weight, ovary weight and insulin resistance markers (insulin and glucose levels and HOMA-IR) were determined. The right ovary was isolated and floated in appropriate fixative. 5-6 μm sections was prepared as paraffine embedding method and stained by H&E and PAS and studied by light microscopy.
Hyperglycemia, insulin resistance and reduced body weight of diabetic rats were improved after administration of Okra for 4 weeks. This effect was relatively similar to metformin. Okra powder was caused a significant increase in primordial, primary and graffian follicles (P The results of the present study revealed that A. esculentus possess antioxidant activities has a potential positive role against hyperglysemi and useful intervention for improvement of ovaian dysfunction in diabetic rats.

Health system development plan has eight steps in the government response to vulnerable demands in the health sector in the community. The quality of services is an important factor for the growth, success and survival of the organization. Therefore, the purpose of this study was to review the health care quality after apply health system in yasuj city hospitals.
population of this descriptive study were 380 patients in Shahid Beheshti hospital, 150 patients shahid rajaee hospital and 300 patients in imam sajjad hospital which selected 181 patients in Shahid Beheshti hospital, 108 patients shahid rajaee hospital and 169 patients in imam sajjad hospital as subject according to Morgan table. All subjects filled out health system design and quality of treatment services questionnaires. For statistical analysis of data used Pearson correlation coefficient and regression tests (p≤0.05).
There is significant relationship between the health system and the quality of health care services (p=0.001) Also quality of health care has significant relationship with reducing the amount paid of patients (p=0.001), supporting the survival of physicians in deprived areas (p=0.001), the presence of specialist physicians residing in public hospitals (p=0.001), improving hoteling quality in hospitals (p=0.001) and improving the quality of the services of visiting hospitals (p=0.001) in the hospitals of Yasuj.
It appears that health care quality after apply health system improved in yasuj city hospitals.

Psychological well-being is a branch of positive psychology, which has been increasingly sought after by psychologists and counselors. Psychological well-being, which is one of the indicators of mental health, is a translation of positive emotions and general satisfaction from one's life and others in different areas of family, education and occupation, and has emotional components as well as cognitive components. The cognitive component represents the individual's satisfaction from life and the individual's assessment of various aspects of life and the emotional component of the interpreter is the relative presence of positive emotions and the absence of negative excitement. This research aims to explain psychological well-being based on attachment to God and psychological well-being.
Non-experimental research and its design were correlated. The statistical population included 328 students in Yasuj University. They were selected by multi-stage cluster sampling. After attending the classroom and obtaining satisfaction and providing the necessary explanations, a questionnaire was provided to them. From scales of attachment to God, Cricket Patrick, psychological well-being of Allen Watterman, and the feelings of shame and guilt of Tajni and Deiring. In this research, after collecting the data, using the questionnaire technique, the final data were extracted and analyzed using the software (Amos) version 24 (spss) version 18.
Those who have a good attachment to God have a favorable psychological well-being. Also, analysis of the results showed that there is a positive and significant relationship between feeling of shame and sin with psychological well-being and attachment to God. Benjamin can be said that attachment to God and the feeling of shame and sin affects psychological well-being and mental health.

Nutritional literacy is skills and the degree capacity of privates to obtain, process and understand nutrition information to make good decisions about nutrition. The use of this information and nutritional services leads to health promotion. This study examined the status of nutritional literacy in elementary school teachers in Yasuj and its related factors.
In this Cross-Sectional study, a questionnaire of 35 items belonging to Turkey was used. After translation-retranslation and determine its validity for assessing nutritional literacy, it is used in 110 persons of elementary school teachers in Yasuj. The samples were selected by multistage stratified sampling and questionnaire was completed for them. The data were analyzed by using descriptive and analytical statistics.
Findings: The average age of participants was 39.48±3.2. The results showed that the mean score of nutrition literacy for participants was 27.14± 3.2. 22.7 percent of teachers had limited or poor nutrition literacy. Teachers with less work experience and bachelor's and higher degree had more nutritional literacy scores. The least number of correct answers was related skills of food centers determination, computing skills and reading of food labels.
Overall, according to the level of nutritional literacy in different parts of the group of teachers, it should be considered the designing of interventions to improve nutrition literacy. Because of its uniqueness in Iran, this questionnaire can be used as needs assessment tool in nutritional interventions in Iranian society.