فهرست مطالب
Journal of Kermanshah University of Medical Sciences
Volume:22 Issue: 3, 2018
- تاریخ انتشار: 1397/08/30
- تعداد عناوین: 6
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Page 1Background
Recurrent pregnancy loss (RPL) is defined as two or more pregnancy losses before 20 weeks gestation. -TNF-α is a pro-inflammatory cytokine that has been proposed a candidate gene for the pathogenesis of RPL. This study aimed to investigate the association of TNF-α-308G/A polymorphism with RPL among East Azarbaijan population.
MethodsThe patient group comprised 100 women with the experience of three pregnancy losses and the control group comprised 100 women without any previous history of pregnancy loss. Genotype TNF-α-308G/A was detected using PCR-RFLP assay.
ResultsThe observed frequencies of GG and GA genotypes of TNF-α-308G/A polymorphism were respectively 84% and 16% in the patient group and 81% and 19% in the control group. AA genotype was not observed in any of the groups.
ConclusionsOur results suggest that the TNF-α-308G/A polymorphism is not associated with RPL in East Azarbaijan women
Keywords: TNF-?-308G, A polymorphism, East Azarbaijan -
Page 2Background and ObjectivesThe quality of life in infertile couples depends on many factors, including dimensions of their sexual relationship. The present study aimed to identify and explain dimensions of sex-related high quality of life in infertile couples.MethodsIn the present qualitative study, data were collected through semi-structured exploratory interviews with 15 infertile couples selected purposively from clients presenting to infertility treatment centers in Yazd. Data saturation was reached in the second interviews. Data were encoded and analyzed by thematic analysis method.ResultsBased on the answers, dimensions of sex-related quality of marital life among infertile couples were categorized in 74 initial concepts, 9 items and 3 themes of “healthy attitude toward sex”, “enriching sex”, and “Managing the effect of infertility on sexual satisfaction”.ConclusionsBased on the results obtained and the dimension of sexual relation in Woods’ conceptual framework, and for a satisfactory sexual life despite infertility, infertile couples should raise their knowledge and pay greater attention to enriching this dimension of their relationship to achieve sexual compatibility along with infertility.Keywords: Dimensions of Sexual Relationship, Marital Quality, Infertile Couples, Qualitative Study
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Page 3BackgroundThe present study aimed to investigate the effects of consuming 6 weeks of beetroot juice (Beta vulgaris L.) on hematological parameters in female soccer players.MethodsTwenty female soccer players were selected randomly and assigned into two groups: Experimental (beetroot juice, n = 10) and control (placebo, n = 10). Subjects trained for six weeks (three 90-min sessions per week) by consuming 200 mL of juice 2 hours prior to training. Blood samples were collected and investigated (Hb, Hct, RBC, Iron, MCV, Ferritin and TIBC) in pre- and posttest. Paired Sample t-test and Independent Sample t-test were used for comparision within and between groups, respectively. Statistical significance was P ≤ 0.05.ResultsResults showed that the experimental group had significant increases in the Hb, Hct, RBC, iron, and ferritin levels (P < 0.05). No significant difference was detected in MCV levels (t = -1.10, P = 0.29) and there was a significant decrease in the TIBC (t = 4.99, P = 0.001). In the control group, there were significant differences in (Hct, iron, ferritin and TIBC) (P < 0.05). In addition, there were significant differences in (Hb, Hct, RBC, iron, ferritin and TIBC) levels between experimental and control subjects (P < 0.05), but there was no significant difference in MCV (t = 1.11, P = 0.28).ConclusionsSince beetroot juice consumption has significant effects on the levels of some hematological parameters in female soccer players, it can be used to prevent and improve anemia among these athletesKeywords: Anemia, Female Adolescents, Beetroot Juice, Soccer
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Page 4Background
Oxidative stress induced by aluminum (Al) toxicity leads to the dysfunction of the hematopoietic system. Detoxifying by means of common chelators causes many side effects. Therefore, researchers have been trying to find safer treatments.
ObjectivesThis study aimed to evaluate the effects of Saccharomyces boulardii and S. boulardii enriched with selenium (Se) on Al-induced toxicity in rats.
MethodsFemale rats were divided into 6 groups: (A) Control group, (B) S. boulardii treatment group, (C) enriched S. boulardii treatment group, (D) Al-infected group, (E) S. boulardii treated and Al-infected group, (F) enriched S. boulardii treated and Al-infected group. At the end of the treatment period, blood samples were taken directly from the hearts of rats in order to measure hematological parameters, total antioxidant capacity (T-AOC), malondialdehyde (MDA) concentrations, iron, and total iron binding capacity (TIBC).
ResultsResults revealed significant increases of white blood cells (WBC), red cell distribution width (RDW), TIBC and MDA in group D as compared to the control group and significant reductions of these factors in groups E and F as compared to group D. T-AOC, iron, and mean corpuscular volume (MCV) decreased in group D as compared to the control group, but significantly increased in groups E and F as compared to group D. Other observed changes were not statistically significant.
ConclusionsIt appears that S. boulardii partly reduced the harmful effects of Al toxicity, especially when enriched with Se due to its antioxidant properties. Further studies are needed in this area.
Keywords: Aluminum Toxicity, Anemia, Oxidative Stress, Selenium, Saccharomyces boulardii -
Page 5BackgroundGiven the significance of sleep quality among pregnant women and its effects on the health of the fetus and pregnant mothers, the present study aimed to investigate the correlation of quality of sleep with repetitive negative thoughts and emotional dysregulation among pregnant women.MethodsIn this correlational descriptive study, 300 pregnant women, residing in Kermanshah and presenting to OB/GYN offices during a month, were selected through convenience sampling. Three questionnaires were utilized for data collection: repetitive negative thoughts, emotional dysregulation, and Pittsburgh sleep quality index (PSQI). Finally, the data was analyzed in SPSS V. 21 and Amos V. 21.ResultsThe results of the present study revealed that all components of emotional dysregulation were positively correlated with quality of sleep, and there were significant relationships between all three components of repetitive negative thoughts and quality of sleep. Further, the results indicated that repetitive negative thoughts could the quality of sleep (0.22) (P < 0.009). However, emotional dysregulation did not have any significant direct effects on the quality of sleep. In other words, emotional dysregulation was found to affect the quality of sleep through repetitive negative thoughts (0.15), (P < 0.01).ConclusionsAccording to the results of the present study, it was concluded that the quality of sleep was reduced by emotional dysregulation when repetitive negative thoughts were high. Therefore, it can be concluded that negative repetitive thoughts have a negative influence on the quality of sleep.Keywords: Quality of Sleep, Pregnant Women, Repetitive Thoughts, Emotional Regulation
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Page 6BackgroundUsed in the dyeing industry, Acid Green 3 has a complicated molecular structure and a low level of biodegradability. The present study investigated the removal of Acid Green 3 from synthetic solutions by UV/S2O8-2.MethodsThis cross-sectional study was conducted at the laboratory scale. The effect of time (5 - 60 min), pH (3 - 11), Acid Green 3 concentration (50 - 150 mg/L), and dose of S2O8 (10 - 50 mg/L) was studied under the UV radiation with 510 mJ/cm2 intensity and 636 nm wavelength. Spectrophotometer (wavelength of 636 nm) was used to measure remaining concentration of Acid Green 3 after each experiment. Linear regression was used to create an appropriate linear model.ResultsResults showed a removal percentage of 95% was achieved under the optimal conditions of the studied variables: pH = 3, Acid Green 3 = 50 mg/L, S2O8-2 = 50 mg/L and time = 60 min. The kinetics of UV/S2O8-2 process for all the investigated variables followed the pseudo-first-order kinetic model. In addition, the removal efficiency of COD for Acid Green concentrations of 50, 100, and 150 mg/L were about 78%, 53%, and 41%, respectively. Linear regression analysis yielded a model with R2 = 0.852 and adjusted R2 = 0.792.ConclusionsIn the current study, the variables of Acid Green 3, S2O8-2, contact time, and pH were effective on the process efficiency. Regarding the high efficiency of UV/S2O8-2, this process could be employed for the removal of Acid Green 3 and similar compounds from industrial effluentsKeywords: Advanced Oxidation, Acid Green 3, Wastewater Treatment, UV, S2O8