Iranian Journal Of Dermatology
Volume:1 Issue: 1, 1997

Warts are among the most common skin diseases especially in children between the ages of 12-16 years. Usually plantar and periungual lesions are resistant to traditional treatments and cause a lot of trouble for patients. The aim of this study was to evaluate therapeutic effects of intralesional Bleomycin injection. This study was performed on 38 cases of recalcitrant warts. All the lesions disappeared by one or two injections during 1-2 months. After one-year follow-up, recurrence was observed in two cases.

Cutaneous leishmaniasis is a parasitic infection prevalent in many areas. The parasitic agent is usually transmitted by Phlebotomous sp. Lip leishmaniasis is a type of cutaneous leishmaniasis, which has rarely been reported. In a retrospective study performed in Ahwaz, center of Khuzestan province, southwest of Iran, 2861 patients were detected during 1986-1996. Seventeen of these patients (0.59%) had lower or upper lip leishmaniasis. The patients, age ranged from 3 months to 40 years. Duration of infection was 2 to 4 months. Eleven patients had only lip lesions whereas 6 patients had one or more skin lesions elsewhere. The appearance of lesions differed from nodules to crusted ulcers, usually observed on the vermilion border. Most of the cases failed to respond to topical or systemic antibiotic therapy. The diagnosis was based on the demonstration of Leishman bodies in Giemsa stained smears.

Behcet’s disease is a multisystem disease characterized clinically by oral aphthae and occasionally by genital aphthae, cutaneous lesions such as pustular vasculitis, sweet syndrome-like, pyoderma gangrenosum-like and erythema nodosum-like lesions and variably present systemic features such as synovitis, anterior and posterior uveitis, meningoencephalitis and large vessel smaller vessel vascular disease, and Aphthae may occur throughout the entire gastrointestinal tract. We studied 26 cases of Behcet’s disease hospitalized in Sina Hospital, Ahwaz. 20 of these patients were woman (76%) and 6 were men (74%), with an age range of 13 to 43 years. All the patients had oral aphthae, 22 had genital aphthae (84%), 8 had eye disease (30%), 10 had skin lesions (34%), 10 had arthralgia and arthritis and 3 had CNS involvement as head ache.

Pachydermoperiostosis (PDP) is a rare hereditary disease characterized by folded coarse skin, hyperostosis, clubbing of fingers and abnormalities in other organs such as gastrointestinal tract. Because of safety parents guides us to familial incidence and penetration of gene in 50% of cases. Diagnosis is based on clinical and radiological findings. Males are more susceptible than females to this disease. This is the report of primary PDP in two brothers whose parents were net affected. Therapy in this syndrome is symptomatic, and using of low dose colchicine was not effective in this case.