فهرست مطالب

فصلنامه یافته
سال یازدهم شماره 1 (پیاپی 34، بهار 1388)

تاریخ انتشار: 1388/03/11
تعداد عناوین: 10

فارسی
English

انتخاب همه

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Evaluation of theophylline clearance in asthmatic or COPD patients admitted to emergency ward of Kerman Afzalipour hospital in 2006

Dr Sm Sohrevardi Page 3

Background
Theophylline is one of the oldest drugs that is used to treat asthma and COPD. Theophylline metabolism can alter by some of the drugs and diseases. Severe theophylline side effects are usually related to plasma concentration higher than 20 mg/L. The present study was done to determine aminophylline clearance and the drug use evaluation in Afzalipour hospital.
Materials And Methods
In this cross-sectional study 21 asthmatic or COPD patients were enrolled. 2 blood samples were drawn at 15 minutes and 24 hrs after completing aminophylline loading dose and starting maintenance dose infusion. Serum theophylline concentration were determined using HPLC and drug clearance was calculated by "Chiou" methods and compared with theophylline clearance based on population pharmacokinetic study.
Results
Mean patients age were 57±18 years. Mean theophylline concentration in the two samples were 9.1±4 and 5.1 ±3.3 mg/L respectively. Our patients clearance was 4.2±2.2 L/hr and there was no statistically significant difference with theophylline clearance (3.1±1) based on population pharmacokinetic study (P=0.075).
Conclusion
Based on our study there was not rational and logical usage of aminophylline in the our patiens. In 62% of the patients’ serum, theophylline level were less than 5 mg/L. It is suggested that Therapeutic Drug Monitoring must be used in patients who receive intravenous aminophylline specifically in the critically ill patients, to prevent drug toxicity and to ensure about drug efficacy.

Abstract View Paper Original: Persian

Outcomes of opiod abstinence after ultra-rapid opiate detoxification (UROD) under general anaesthesia

Dr H. Teimory, Dr F. Sabzi Page 9

Background
Opiod dependency has serious socioeconomic disadvantages in addition to physical damage. Various methods are used to increase abstinenece rate of opiod dependency, among which UROD under general anesthesia is the new one which leads to reduce withdrawal syndrome and symptoms.
Materials And Methods
This cross-sectional study was done to evalute opiod abstinence rate by UROD on 121 patients referred to Khorramabad Shohada Ashayer hospital in 2005. After interview and obtaining written informed consents, all patients underwent general anaesthesia for 5 hours with 0-25 to 0.5 mg/kg IV Naloxane. Then all patients followed at 4-6 months after UROD for relapse of addiction by self report and three coincidental tests of addiction. Data was analyzed by SPSS software version 9.1.
Results
The results showed that opiod abstinence rate at a 4-6 month follow up among 104 eases out of 121 addicts undergone UROD was 86.5%. Abstinence rate had no significant relationship with age, level of education, duration, way of use and kind of opiod, but it had a significant relation with employment status(p<0.001).
Conclusion
It seams that UROD can reduce the withdrawal syndrome and symptoms, and prevents the relaps of addiction.

Abstract View Paper Original: Persian

A comparative study of high school student's attitude and knowledge towards Ecstasy in risky and non risky areas in Khorramabad in 2006

Dr M. Safa Page 23

Background
The investigation done in recent years have shown considerable prevalence of ecstasy abuse as a drug desirable for the youth. The present study tries to view the high school student's knowledge and attitude towards Ecstasy in risky and non- risky areas in Khorramabad city.
Materials And Methods
In this study, a 200 male and female students were selected using random multiphase sampling. A questionnaire with 50 items was used as data gathering tool. The data were analyzed using statistical variance.
Results
The results showed that in risky areas of the city 6.2 % of the subjects had positive attitude towards ecstasy and 45.45 % had highly negative attitude. In non risky areas 2% of the subjects had positive attitude and 8.2 % had highly negative attitude towards ecstasy.In surveying the degree of knowledge and awareness towards ecstasy,44.29% of the subjects in risky areas had poor knowledge and 7.1% had high level of knowledge.In non risky areas 48.5% had poor knowledge and 42.5% had average and 5% had high level of knowledge towards ecstasy. The analyzed data showed that there was no significant relationship between the students’ attitude and level of knowledge with their parent's job, education, sex, age and the number of siblings.There was a significant relationship between student's level of knowledge and their school performance while these two variables had no relationship with student's attitude.
Conclusion
Based on the obtained findings, it is suggested that responsible bodies improve and enhance the public knowledge of people by the mass media. This matter should be emphasized more in risky areas.

Abstract View Paper Original: Persian

Adding omega-3 to mainenant antidepressant therapy in recurrent depressive disorder

Dr M. Jaryani, Dr H. Nazari Page 31

Background
Depression is one of the most common psychological disorders. Most depressed patients experience multiple recurrences despite the pharmacologic therapy. Many studies have reported that countries with high rates of fish consumption have low rates of depressive disorder. The aim of present study is to evaluate the effect of omega-3 as a complementary treatment on the patients with recurrent unipolar depressive disorder who were receiving maintenant antidepressant therapy.
Materials And Methods
In a clinical trial, eighty patients with a diagnosis of recurrent major depressive disorder were divided into two groups of forty. One group received standard anti-depressive therapy (with SSRIs) and the other received omega-3 in addition to standard therapy.
Results
Findings of the study showed that adding omega-3, significantly reduced depression score and increased patients’ function.
Conclusion
Results showed that omega-3 can be added to the standard treatment in patients with recurrent and refractory depressive disorder as complementary treatment.

Abstract View Paper Original: Persian

Survey of school backpack's standards in Khorramabad primery school students (2007-2008)

Dr F. Tarhani Page 49

Background
A large number of students tend to carry school backpacks. Carring heavy backpacks is increasingly putting the students at risk, and may cause long term damage to their growing body. This survey was conducted on Khorramabad primary school students to determine if their backpacks are too heavy and the methods of packing and wearing them, and history of back pain among them.
Materials And Methods
This Cross – sectional Study included taking 1009 students, Weighting them and their backpacks, While asking about Packing and wearing methods and the history of back pain.
Results
The results showed that backpacks were heavy in 57/8% of the cases. 24/6% had history of back pain and there were significant relationships between the carrying heavy backpacks and wearing them improperly, and the history of back pain.
Conclusion
The main conclusion in this study was that many students are carrying heavy backpacks and packing and wearing them improperly which put them at risk of back pain and other complications.

Abstract View Paper Original: Persian

Study of HIV & HCV coinfection in suspected patients referred to Khorramabad Shohadaye Ashayer hospital in 2007

M. Mohammadi Page 57

Background
Because of predisposing risk factors, prevalence of HIV & HCV in different countries has been reported with different percentages. Co infection of HIV & HCV in patients could have additional effects on infection process, persistence and prevalence rate. The purpose of this study was assessing prevalence rate of these infections especially co infection of HIV and HCV in patients.
Materials And Methods
This descriptive and cross sectional study, was carried out on suspected patients of HIV and HCV referred to Khorramabad Shohadaye Ashayer hospital, in 2007. Patients’ serums were evaluated by ELISA for the presence of specific Antibodies. Collected data was analyzed using SPSS software. Fisher's exact test with 5% error intervals was used for correlation of sex and infections rate.
Results
304 and 116 of cases were men and women respectively. Results of the study indicate that 45(10.7%) of the cases were HIV positive (10% men and 0.7 % women) and 115 (24.8%) cases were HCV positive (20.3% men and 4.5% women). Co infection rate for HIV and HCV was 8.1 % out of 420 total cases. 75.6 % of HIV positive cases were co infected with HCV. Co infection of HIV with HCV was significantly correlated. (p <0.001)
Conclusion
Because of high prevalence of HCV co infection in HIV patients it's likely that HIV positive individuals have greatest risk of acquiring HCV infection and vice versa. Co infection rate of HIV & HCV in our country may be higher than other countries.

Abstract View Paper Original: Persian

A survey on determining the total coliforms bacteria in the process of ice production in kerman ice-manufactucturing houses

Dr M. Malakootian, Dr Gh Shams Page 65

Background
Pathogene transmission by ice, which has been attended for many years, is as important as its transmission by water. Ice infection is caused by using water distribution and translocation methods. The aim of this study is to evaluate microbial infections (Choliform variants) in ice making procedure at ice manufacturing houses in Kerman Province cities.
Materials And Methods
This study was cross-sectional and census method was used as data collecting method. Sampling was done in the first half of the year 2008 so that Choliform bacterial situation in four ice manufacturing houses at the cities of Kerman was evaluated. Water and ice samples collected from three different process of ice-making (entrance, processing, exit). Samples were taken in the first two-month of Spring and last month of Summer (each month, ten times).
Results
Results showed that 27 samples out of 120 samples had Choliform infection. Minimum infection was related to entrance process (approximately 7.5%) and maximum infection related to exit process (approximately 37.5%).
Conclusion
Results of the experiments showed that all of the ice manufacturing houses had Choliform infection. The least infection belonged to ice manufacturing house No 1 (18.18%) and the most infection related to ice-manufacturing houses No 2 and 4 (25% for each one (. This study showed that in spite of low contamination in entrance stage of water, there existed a high contamination in produced ice. Findings of this study showed that environmental contamination of ice-manufacturing houses and staff working there, can play an immense role in dissemination of bacteria, as well as water-borne diseases, so it is recommended to pay more attention to staff personal hygiene and environmental health of ice-manufacturing houses to reduce the risk of contamination

Abstract View Paper Original: Persian

Study of heavy metals concentration Cd, Cr, Pb and Ni, in cultured ponds fishes of Khorramabad city in 2006

Gh Asgari Page 73

Background
The consumption of aquatic nutrition sources, especially fishes, considered as a partial supply of protein, for ever-increasing demand of protein. According to statistics, the annual consumption of aquatic sources per capita in the word increased from14. 3Kg in the year1994 to more than 15. 75 Kg in 1997 and in Iran it increased from less than 1 kg in the year 1978 to 4.57 kg in the year 1996. So an ever-increasing demand of protein sources of the food and bioaccumulation of toxic compound especially toxic heavy metals increase safety control importance of the food. In this descriptive cross-sectional study heavy metals concentration Cd, Cr, Pb and Ni in cultured ponds fishes of Khorramabad city were studied in 2006.
Materials And Methods
To evaluate the safety of the cultured ponds fishes in khorramabad city from toxic heavy metals Cd, Cr, Ni and Pb, 240 samples of fishes were collected. The fishes were collected in the Spring and Summer seasons in 2006. The samples washed and digested with acid before using Atomic Absorption for determination of the metals, then data were analyzed using t-test and SPSS software.
Results
The results of the study showed that the average value of Lead, Chromium, Cadmium and Nickel in ten cultured ponds fishes tissue were 0. 46, 0. 06, 0. 053 and 0. 30 ppm (dry weight basis) respectively The study also showed that the amounts of Pb in 27%, Cd in 8%, Cr in 3% and Ni in 25% of the samples exceeded the WHO standard limits while the averages were blow the standard.
Conclusion
The statistical analysis of the samples showed that there are not significant differences between the different species of the fishes for all the heavy metals, except the fishes collected from the cultured ponds. Higher amount of the heavy metals in sea fishes could be related to fish food, which could bioaccumulated in fish tissues. The study revealed that non of the heavy metals collected in the fish samples exceeded the WHO standards.

Abstract View Paper Original: Persian

An Asthma mimicker air ways tumor: report of a rare case of schwonnoma

Dr Sa Tabatabei, Dr Sm Hashemi Page 81

Background
Primary schwannoma of trachea and bronchus is very rare and can cause the same signs and symptoms as asthma, including airway-obstruction. Case Report: We introduce a 17 years-old girl with left bronchus schwannoma who was under treatment with the primary diagnosis of asthma and allergy. Bronchoscope intervention showed a pedicular tumor in left bronchus which protruded from the orifice of bronchus during hale and inhale leading to more than %80 lumen obstruction of airway.
Discussion
The patient underwent surgical treatment of tumor resection and bronchoplasty along with long survival. Following this operation, all signs and symptoms were resolved. Therefore we should be aware that tumors, even this rare one should be considered as a differential diagnosis in patients suffering from airway obstruction, especially when children and young adults dont response to usual treatments. Keywords:

Abstract View Paper Original: Persian

علمی مصوب

فصلنامه یافته

Yafteh

فصلنامه پزشکی

آخرین شماره | آرشیو

ISSN: 1563-0773

صاحب امتیاز:

دانشگاه علوم پزشکی لرستان

مدیر مسئول:

دکتر حسن تیموری

سردبیر:

دکتر سهیلا اکبری
تلفن نشریه: ۰۶۶-۳۳۱۲۰۲۳۳

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فهرست مطالب

فصلنامه یافته سال یازدهم شماره 1 (پیاپی 34، بهار 1388)

فصلنامه یافته

Yafteh

فصلنامه یافته
سال یازدهم شماره 1 (پیاپی 34، بهار 1388)