فهرست مطالب

مجله دانشگاه علوم پزشکی شهرکرد
سال ششم شماره 1 (پیاپی 21، بهار 1383)

80 صفحه،
تاریخ انتشار: 1383/02/15
تعداد عناوین: 10

فارسی
English

انتخاب همه

Antibiotic susceptibility among antibiotic resistant salmonellae isolated from children (0-2 years) affected by diarrhea in Shahrekord and resistance factor transmissibility to E.Coli k12

Ali Sharifzadeh, Farhid Hmatzadeh, Abdolrasool Namjoo, Azar Danesh Page 1

Background And Aim
The aim of this study was to detect the dominant serotypes of salmonellae in children and to find the antibiotic susceptibility and R-factor transmissibility among isolated salmonellae.
Method
This study was conducted on 400 diarrheic stool samples collected from children in Ayatollah Kashany hospital of Shahrekord, during spring of 1999 to autumn of 2000.
Results
After isolation and identification of salmonellae, seven serotypes were detected. One of them was S. typhi and other the six serotypes were S. paratyphi B. Then biogram test was performed by disk diffusion method. Best Results were taken from ceftizoxim, cephtriaxon, cephazolin and chloramphenicol. The R-factor had been transferred from isolated salmonellae to penicillin and ampicillin.
Conclusion
Results substanciate that unnessessary usage of antibiotics, which is the main cause of drug resistance, should be prevented.
Keywords: Antibiotic resistance, Children diarrhea, Resistance transmissibility, Salmonellosis

Abstract View Paper Original: Persian
Investigation of cancers incidence relevant to radiation in Chaharmahal and Bakhtiari province during five years (1998-2002

Daruesh Shabazi, Azar Danesh Page 7

Background And Aim
The induction of cancer appears to be the most important effect of low-dose ionizing radiation occurring in an exposed population. The major cancers induced by whole-body radiation exposure are the breasts in women, thyroid, lung, skin cancers and leukemia. In developing countries 94% of the human radiation is from the natural sources. In Iran some high altitude regions such as Chaharmahal & Bakhtiari has a high level of the natural background radiation (higher than the world’s average). For this reason, investigation of the incidence of cancer, relevant to the radiation is very important in this province which is the aim of this study.
Method
In this study 751 cases suffering from malignant cancer (based on ICD10) were investigated during a 5-year period (from 1998 to 2002). Three hundred sixty-two cases suffering from skin, breast, lung, thyroid cancers or leukemia were selected. All data was obtained from health centers and pathological sections of relevant hospitals. Chi-square test was used for data analysis.
Results
The prevalence of skin, breast, thyroid and lung cancers and leukemia as compared with total recorded cancers were about 20.5%, 7.5%, 2.6%, 1.1% and 16.2%, respectively. From all studied cases, 48.3% were male and 51.7% were female. There was significance relationship between sex and the cancer type (p<0.05). The mean age of patients with skin, breast, thyroid and lung cancers and leukemia were found to be 62.98, 51.14, 44.6, 60.89 and 33.8 years, respectively. The total radiation induced cancer risk was greater for women than for men.
Conclusion
The prevalence of skin, thyroid cancers and leukemia in this province was more than the other areas of Iran due to the high levels of the natural background radiation in this province.
Keywords: Breast cancer, Lung cancer, Leukemia, Natural background radiation, Skin cancer, Thyroid cancer

Abstract View Paper Original: Persian
The effect of psychical stress on cause and exacerbation of diabetes mellitus, serum glucose and cortisol levels, and body weight in rats

Mariam Radahmadi, Tarokh Shadan, S. Shahabdin Sadr, S. Morteza Karimian Page 14

Background And Aim
In this study the effects of chronic stress on the serum glucose level (SGL), serum cortisol level (SCL) and body weight were investigated to determine the possible causal link between stress and diabetes.
Method
The experiments were performed on nondiabetic and diabetic rats divided to control, sham, and stressed groups. Water immersion was used as chronic psychical stress (one minute every hour, 4 hours every day for a period of 14 days). After the experiment, a blood sample was collected. The serum glucose level was measured by the glucose oxidase method, and serum cortisol level was measured by radioimmunoassay method. Difference in body weight was also calculated.
Results
Our results showed that, this psychical stress caused a significant increase in glucose level in both nondiabetic and diabetic rats, but could not produce diabetes in nondiabetic rats. Diabetes caused significant increase in serum cortisol level. This stress caused a small but nonsignificant increase of cortisol level. Also, there was a significant weight loss in stressed rats, that was much higher in diabetic rats. Effect of diabetes on weight loss was much higher than that of the psychical stress.
Conclusion
Therefore stress exacerbated the disease in the diabetic rats and probably made the nondiabetic rats prone to diabetes.
Keywords: Body weight, Cortisol level, Diabetes mellitus, Glucose level, Psychical stress

Abstract View Paper Original: Persian
Reduction of colonization of Enterotoxigenic Escherichia Coli (ETEC) in mice by Probiotic (Lactobacillus casei

Sali Fazeli, Hajeih Ghasmian, Reza Mirnzhad Page 26

Background And Aim
Diarrhea still is one of the major health problems in many parts of the world. In developing countries Enterotoxigenic Escherichia coli (ETEC) is a major cause of severe disease in children and it is the most frequent cause of traveler’s diarrhea. Diarrhea caused by ETEC is dependent on its colonization in the small intestine, thus reducing its colonization can potentially reduce the disease. Probiotics are microorganisms (bacteria and yeasts) that have beneficial effects on the health of the host when ingested. The purpose of this study was to use the Lactobacillus casei as a probiotic organism for reducing the shedding and colonization of ETEC in the Balb/c mouse intestine.
Method
The mice allocated into either a probiotic-treated group or a control group. The treated group were given probiotic (1×108cfu) for either 3 or 6 days, and the control group were not given any probiotic. Seventy-two hours after the last oral administration of probiotic, the test and control mice were challenged with ETEC (1×108cfu). Frequency of shedding was evaluated by colony counting of fecal samples.
Results
The results indicated that mice given probiotic for 3 or 6 days had a significant reduction in the frequency of ETEC shedding (p<0.001) compared to the control group.
Conclusion
The findings suggests the Lactobacillus casei as a possible candidate for a probiotic against Enterotoxigenic Escherichia coli.
Keywords: Balb, c mouse, Enterotoxigenic Escherichia Coli (ETEC), Lactobacillus casei, Probiotic, Traveler's diarrhea

Abstract View Paper Original: Persian
A case report of Asyptomatic rupture of a rudimentary uterine horn in a patient with nephrotic syndrome

Mariam Khooshideh Page 34

Background And Aim
Pregnancy in a noncommunicating rudimentary uterine horn frequently results in rupture. Uterine rupture usually causes a massive intraperitoneal hemorrhage, necessitating emergency operative intervention to control bleeding.
Results
This article is a report of an unusual pregnant patient who had severe nephrotic syndrome with an anomaly in uterus and asymptomatic rupture of a rudimentary horn. Also gestational age at the time of the occurrence of the rupture was more than other cases that have been reported.
Keywords: Intraperitoneal hemorrhage, Rudimentary horn of uterus, Uterine rupture

Abstract View Paper Original: Persian
Epidemiology of burn patients in Emam Reza Hospital, Birjand, 1998- 2002

Shahnaz Tabiee, Mariam Nakhaee Page 43

Background And Aim
Burn injuries still produce a significant morbidity and mortality in Iran and other countries. This cross-sectional study was carried out to find the epidemiology of burn patients admitted to Birjand Emam Reza Hospital burn unit.
Method
Medical records of 342 patients were assessed for demographic and burn characteristic data.
Results
The results indicated that the 13.7% of the patients were hospitalized with a mean age of 23.1 years, and 55.6% of them were men. The mean BBS (Body Burn Surface) and mortality rates were higher in females. Most of the burn injuries were caused by domestic accidents (83.9%). Self-inflicted burns were higher in females (63.9%) and in 10-30 years old patients. There was significant correlation between mortality rate and age groups, gender as well as BBS (p<0.001). Among the prognostic factors in our study, self-inflicting (O.R:12.2608; CI:4.2600-35.2884) and BBS more than 40% (O.R:31.6546; CI:13.7134-73.0682) were identified as strong predisposings to death.
Conclusion
Regarding to high-risk groups (children and young adults), prognostic factors and high mortality rate (%29.8) in burn patients, implementation of public educational programs for prevention and continuos education for care provider teams are essential.
Keywords: Birjand, Burn, Epidemiology

Abstract View Paper Original: Persian
Sympathetic skin response in chronic renal failure patients

Behrooz Kazemi, Smostafa Jzayeri, Smohamadhosin Arad Page 52

Background And Aim
Uremic neuropathy is one of the most common complications of chronic renal failure. Autonomic neuropathy occurs in addition to peripheral somatic system involvement. Sympathetic skin response (SSR) is a simple noninvasive test for evaluation of skin’s eccrine sweat glands activity in response to sympathetic stimulation. Pathway of this sympathetic response contains afferent myelinated fibers, central part and efferent unmyelinated sympathetic fibers.
Method
In this study SSR test was performed on 31 patients with chronic renal failure on regular hemodialysis and 35 normal controls.
Results
SSR was absent in 12 patients (38.7%) and abnormal in 23 patients (74%). No good correlation was found between abnormal SSR and clinical dysautonomic symptoms, but it seems that SSR becomes abnormal long before appearance of clinical dysautonomic symptoms in chronic renal failure. Age, Sex, duration of hemodialysis and duration of history of renal failure had no effect on SSR, but SSR seems to be affected by high weekly frequency of hemodialysis.
Conclusion
So we concluded that in chronic renal failure peripheral sympathetic system involvement is common and adequate dialysis has effect on its progression.
Keywords: Autonomic neuropathy, Chronic renal failure, Sympathetic skin response

Abstract View Paper Original: Persian
Respiratory symptoms and gastroesophageal reflux in adult population of more than 20 years old in Shahrekord

Smohamad Kazem Hosine Asl, Babak Amra Page 58

Background And Aim
Association between gastroesophageal reflux (GER) and respiratory diseases has been known for a long time. There are few epidemiological studies on general population in the world, and little is known about a possible association between respiratory symptoms and reflux in Iran.
Method
A sample of 5492 adults (more than 20 years old) was randomly selected for the study, from them 4762 subjects agreed to take part (86.7%). The medical students interviewed all of the subjects.
Results
The prevalence of monthly reflux symptoms and active asthma were 25.5% and 6.7% respectively. The correlation between reflux and asthma had a confidence interval of (2.60–3.43) and an odds ratio of 2.99. The correlation between chronic bronchitis and reflux had a confidence interval of (1.43–2.58) and an odds ratio of 1.92.
Conclusion
These findings indicates that epigastric pain in many asthmatic and chronic bronchitis patients may be due to reflux.
Keywords: Asthma, Chronic bronchitis, Epidemiology, Gastroesophageal reflux

Abstract View Paper Original: Persian

علمی مصوب

مجله دانشگاه علوم پزشکی شهرکرد

Journal of Shahrekord University of Medical Sciences

فصلنامه پزشکی

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eISSN: 2717-0071

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دانشگاه علوم پزشکی شهرکرد

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دکتر مرتضی هاشم زاده چالشتری

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دکتر اسفندیار حیدریان

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فهرست مطالب

مجله دانشگاه علوم پزشکی شهرکرد سال ششم شماره 1 (پیاپی 21، بهار 1383)

مجله دانشگاه علوم پزشکی شهرکرد

Journal of Shahrekord University of Medical Sciences

مجله دانشگاه علوم پزشکی شهرکرد
سال ششم شماره 1 (پیاپی 21، بهار 1383)