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Annals of Military and Health Sciences Research - Volume:16 Issue: 2, spring 2018

Annals of Military and Health Sciences Research
Volume:16 Issue: 2, spring 2018

  • تاریخ انتشار: 1397/04/20
  • تعداد عناوین: 5
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  • Simon Allen * Page 1
    Background
    Innovative thermobalancing therapy (TT) with Dr Allen’s therapeutic device (DATD) treats affected organs by the energy of one’s own body. 10 years empirical evidence has shown that the use of DATD helps to recover from chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) and benign prostatic hyperplasia (BPH), and to dissolve kidney stones. Moreover, the cost of DATD compares favourably with the cost of conventional treatments.
    Objectives
    The purpose of this study is to point to the introduction of TT from DATD to the Primary Health Care system. Methods and Results: Two clinical trials observed dynamics of urinary symptoms by International Prostate Symptom Score (IPSS), quality of life (QoL), ultrasound prostate volume (PV mL) and uroflowmetry (maximum flow rate, Qmax mL/s) in men with BPH and chronic prostatitis. These trials have explored that TT with DATD reduced: prostate volume from 45 mL to 31 mL (P < 0.001) and, consequently, lower urinary tract symptoms, from 14.2 to 4.9 (P < 0.001) in the treatment group 124 patients with BPH; and pain score, from 10.38 to 3.58 (P < 0.001), and decrease of prostate volume from 31 mL to 27 mL (P < 0.001) in the treatment group of 45 men with CP/CPPS. The QoL improved in both treatment groups significantly. In the control groups: in 124 men with BPH in watchful waiting, and in 45 men with chronic prostatitis on standard treatment, no significant difference in parameters was observed. 10 years empirical evidence showed that DATD treats both kidneys simultaneously, dissolving kidney stones, despite their size and type.
    Conclusions
    The outcomes of clinical studies and empirical evidence demonstrated the high effectiveness of TT, which was prescribed as mono-therapy. This therapy is side effects free. It is easy to use Dr Allen’s device, which is a class 1 medical device that doesn’t require involvement of a notified body. Therefore, TT with DATD should be implemented in the primary health care system as a self-managing treatment for chronic diseases.
    Keywords: Chronic Diseases, Chronic Pain, Thermobalancing Therapy, Enlarged Prostate, Kidney Stones, Healthcare, Chronic Prostatitis
  • Hamideh Dehghani Mohammadabadi , Sirous Azizi*, Afsaneh Dadarkhah , Zahra Reza Soltani Page 2
    Background
    Carpal tunnel syndrome (CTS) is the most common entrapment neuropathy in the upper limbs. Conservative treatment is important in reducing signs and symptoms as well as improving the function of patients with mild and moderate CTS.
    Objectives
    The aim of this study was to compare the therapeutic effect of wrist mobilization with local corticosteroid injection in patients with moderate CTS.
    Methods
    This study was a single-blind study that was performed on 58 hands with moderate CTS. Patients were randomly assigned into two treatment groups with 29 samples. Group 1 was treated with local corticosteroid injection (1 cc Methylprednisolone acetate 40 mg + 0.5 cc lidocaine 2%) in the carpal tunnel. Group 2 was treated with carpal bone and median nerve mobilization at the wrist for 10 sessions, about three weeks. Both groups received wrist splints and oral medication (gabapentin capsule 100 mg and vitamin B6 tablet 40 mg per day) for two months. For evaluation of the outcomes, electrodiagnostic parameters of the median nerve (sensory and motor latency and amplitude) before and two months after treatment and also pain intensity (based on visual analogue scale), symptom severity and functional status (based on Boston carpal tunnel questionnaire) before as well as one and two months after treatment, were used. In addition, in long-term evaluation, patient satisfaction was monitored by telephone six months after treatment.
    Results
    Significant improvement was observed in electrodiagnostic parameters two months after treatment and pain intensity, symptom severity, and functional status one and two months after treatment in both groups (P < 0.05); here was no significant difference between the two groups. In addition, in the telephone assessment of patient satisfaction after 6 months, there was no statically significant difference between the two groups.
    Conclusions
    Our results showed that wrist mobilization at the wrist can be effective in reducing signs and symptoms of moderate CTS such as local corticosteroid injection. In addition, these two methods of combination therapy may be used to prevent or postpone disease progression and surgical intervention.
    Keywords: Carpal tunnel Syndrome, Conservative Treatment, Wrist Mobilization, Local Corticosteroid Injection
  • Maryam Koopaie*, Faezeh Esmaily , Mohammad Javad Kharazifard Page 3
    Background
    Herpes simplex virus type 1 (HSV-1) as a member of the herpes virus family recurs in 25% of infected patients 1 - 4 times a year. Reactivation of the virus in the oral mucosa is triggered by stress, sunray, menstruation and trauma to the face.
    Objectives
    The current study aimed to evaluate the effect of fixed prosthetic treatment and root canal therapy on symptomatic and asymptomatic shedding of HSV-1 virus into the saliva.
    Methods
    Twenty two patients with a history of recurrent herpes simplex infection were selected, 11 of whom underwent endodontic treatment and 11 received fixed prosthesis treatment. Saliva samples were obtained immediately before and three days after spitting method of collection. The samples were stored at -70°C and then examined via the polymerase chain reaction (PCR) technique in order to detect probable shedding of the virus.
    Results
    In general, 72.7% (P = 0.09) and 63.6% (P = 0.09) of the samples were positive for HSV-1 in the endodontic and fixed prosthesis groups, respectively.
    Conclusions
    The results of this study indicated that dental treatment could be considered as a risk factor for asymptomatic recurrence of HSV-1 virus in the oral cavity. Therefore, to prevent HSV infection, the use of infection control measures and prophylactic antiviral therapy is critical in immunocompromised patients.
    Keywords: PCR Test, Dental Treatment, Oral Shedding, Herpes Simplex Virus
  • Leila Fozouni *, Fatemeh Taghizadeh , Elahe Kiaei Page 4
    Background
    Malassezia is a dimorphic and lipophilic fungus that causes skin diseases in opportunistic conditions.
    Objectives
    The aim of the present study was to investigate the antimicrobial activity of Aloe vera extract on growth of clotrimazole-resistant Malassezia furfur isolated from patients with seborrheic dermatitis.
    Methods
    In this descriptive cross-sectional study, 102 samples were selected from skin lesions of suspected cases of seborrheic dermatitis. Malassezia isolates were identified by biochemical tests. To determine drug sensitivity, the broth microdilution method was used. After preparation of Aloe vera extract, the antifungal effect of different concentrations of this extract on clotrimazole-resistant isolates was determined by uing the agar well diffusion method, and its minimum inhibitory concentration (MIC) was evaluated by the broth microdilution method.
    Results
    In this study, 72 strains of Malassezia were isolated, out of which the highest frequency belonged to Malassezia furfur with a frequency of 56 (77.8%) cases, while 50% of them were resistant to clotrimazole. Upon evaluation of antifungal effects of Aloe vera extract, the maximum inhibition zone diameter was seen for the extract in the concentration of 250 mg/mL. This parameter was observed for yeast isolates resistant to clotrimazole at the mean of 25 mm. Changes to the MIC of Aloe vera extract in the range of 1024 - 2 μL/mL showed that 89% of Malassezia furfur isolates resistant to clotrimazole did not grow in concentrations with MIC ≥ 512 μL/mL (P < 0.001).
    Conclusions
    According to our results, Aloe vera extract showed proper inhibitory effects against clinical clotrimazole-resistant Malassezia furfur isolates at high concentrations. Therefore, we could hope to treat fungal diseases by producing an appropriate herbal medicine.
    Keywords: Seborrheic Dermatitis, Malassezia, Clotrimazole, Aloe vera, Traditional Iranian Medicine
  • Parvin Zareian*, Roha Mazlom , Laya Ghahari Page 5
    Objectives
    Chronic stress can induce dyslipidemia that promotes atherosclerosis. The aim of this study was to assess the effects of chronic unpredictable stress (CUS) on aorta structure and blood lipids as well as body weight in young and old rats.
    Methods
    Young and old rats were treated with chronic unpredictable stress (for eight weeks) to evaluate plasma lipids and aorta structure. Thickness and internal diameter of aortic tissue were assessed by the ImageJ software.
    Results
    Stress decreased body weight gain in young rats (P < 0.05). Triglyceride, low density lipoprotein (LDL), very low density lipoprotein (VLDL) levels and low density lipoprotein/high density lipoprotein (LDL/HDL) ratio were more in old rats than young rats (P < 0.05). Stress significantly decreased serum triglyceride level in old rats (P < 0.05). Stress significantly increased VLDL level in young (10.3 ± 1.3 mg/dL versus 16.4 ± 2.1 mg/dL) and decreased VLDL level in old (10.8 ± 0.8 mg/dL versus 17.6 ± 1.6 mg/dL) rats (P < 0.05). The inner diameter of aorta was smaller in old (34.5 ± 1.7 micrometers) than young (42.3 ± 1.2 micrometers) rats (P < 0.01). Stress significantly increased inner diameter of aorta in old (42.3 ± 2.1 micrometers versus 34.5 ± 1.7 micrometers) rats (P < 0.01). Aortic wall thickness/aortic inner diameter ratio (AWT/AID) was greater in old rats than young rats.
    Conclusions
    It seems that CUS has a dual effect on serum lipids and aortic diameter in young and old rats.
    Keywords: Chronic Unpredictable Stress, Aorta, Lipid, Aging