فهرست مطالب

Archives of Iranian Medicine - Volume:20 Issue: 10, Oct 2017

Archives of Iranian Medicine
Volume:20 Issue: 10, Oct 2017

  • تاریخ انتشار: 1396/08/30
  • تعداد عناوین: 8
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  • Soraya Saleh Gargari, Farahnaz Torkestani, Vahid Eidkhani, Afshin Amini, Ali Kabir* Page 626
    Background
    By organizing birth weights according to gestational age at birth, reference weight values for different sex-gestational ages are provided.
    Methods
    Data of 1,090,779 mothers and their neonates were gathered from 30 provinces of Iran. Pregnancy complications, maternal risk factors, type of delivery, maternal outcome, neonatal sex and APGAR score were determined. Birth weights were quantified into 3rd, 50th and 97th centile. Regression analysis was used to estimate birth weight of neonates.
    Results
    Birth weight showed an enhancing trend with age; boys weighed more, multiparous women had higher neonatal birth weight, mothers with cardiovascular disease and diabetes mellitus had heavier infants, and mothers aged below 20 years had lower estimated infant birth weight. Gestational age (beta = 147.3) and male sex (beta = 114.9) were the most important independent variables, respectively for predicting birth weight (R-square = 0.512 and P
    Conclusion
    A national reference for fetal growth patterns and related factors was determined in this study.
    Keywords: Birth weight, delivery, fetal development, obstetric
  • Mehdi Yaseri, Mohsen Afarideh, Mostafa Hosseini*, Mahmoud Yousefifard, Ali Rafei, Jalil Koohpayehzadeh, Fereshteh Asgari, Koorosh Etemad, Mohammad Mehdi Gouya, Sina Noshad, Mohsen Bagheri, Neamatollah Ataei Page 633
    Background
    To determine the rate of zero and five end-digit preference (EDP) for systolic and diastolic blood pressures (SBP and DBP, respectively) and risk factors amongst a representative sample of Iranian adults in the year 2011
    Methods
    Data gathered from 7997 Iranian adults aged 25–70 were extracted from the database of the sixth Survey of Surveillance of Risk Factors of Non-communicable Diseases, which surveyed a total of 11,864 individuals aged 6 to 70 years. Multilevel multiple logistic regression was used to identify the independent factors associated with zero or five EDP.
    Results
    The prevalence of three serial zero or five EDP for SBP and DBP were 18.5% (95% CI: 11.3%–25.7%). SBP ≥140 mmHg (OR = 0.78; 95% CI: 0.65–0.95), DBP ≥90 mmHg (OR = 0.71; 95% CI: 0.58-0.88), and a positive family history of diabetes (OR = 0.77; 95% CI: 0.66–0.9) were found as protective factors against zero or five EDP in blood pressure recording the male gender (OR = 1.18; 95% CI: 1.04–1.35) was found to be its independent risk factor.
    Conclusion
    Sex, SBP, DBP and family history of diabetes were found to be the main independent determinants of EDP in our country which underscores the importance of assessing the many patient-related factors in the studies involving EDP as part of BP monitoring in public health care.
  • Mehri Jamilian, Maryam Maktabi, Zatollah Asemi* Page 640
    Background
    There is scarce data on the effects of magnesium-zinc-calcium-vitamin D co-supplementation on glycemic control and markers of cardio-metabolic risk among women with polycystic ovary syndrome (PCOS). The objective of this study was to assess the effects of magnesium-zinc-calcium-vitamin D co-supplementation on glycemic control and markers of cardio-metabolic risk in women with PCOS.
    Methods
    Sixty PCOS women were randomized into two groups and treated with 100 mg of magnesium, 4 mg of zinc, 400 mg of calcium plus 200 IU of vitamin D supplements (n = 30) or placebo (n = 30) twice a day for 12 weeks. Glycemic control and markers of cardio-metabolic risk were assessed at baseline and at the end of trial.
    Results
    After the 12-week intervention, compared with the placebo, magnesium-zinc-calcium-vitamin D co-supplementation supplementation resulted in significant reductions in serum insulin levels (-1.9 ± 4.6 vs. .4 ± 2.8 µIU/mL, P = 0.01), and homeostatic model of assessment for insulin resistance (-0.4 ± 1.0 vs. .1 ± 0.6, P = 0.02), as well as a significant increase in quantitative insulin sensitivity check index (.01 ± 0.02 vs. -0.0003 ± 0.01, P = 0.02). In addition, magnesium-zinc-calcium-vitamin D co-supplementation significantly decreased serum triglycerides (-26.5 ± 42.9 vs. .9 ± 17.9 mg/dL, P
    Conclusion
    Overall, the results of this study demonstrated that magnesium-zinc-calcium-vitamin D co-supplementation for 12 weeks among patients with PCOS had beneficial effects on insulin metabolism and markers of cardio-metabolic risk.
  • Ali Karakus*, Guven Kuvandik, Ezgi Atalay Page 646
    Objective
    In this study, we aimed to review cases with firearms injury of extremities presented to our hospital.
    Methods
    After approval by Institutional Board, electronic database was retrospectively screened for firearms injury of extremities between 2012 and 2015. Overall, 600 cases with firearms injury of extremities were included in the study. Cases were assessed for demographic and clinical characteristics, Mangled extremity severity score (MESS), Glasgow Coma Scale (GCS), costs and outcomes.
    Results
    Totally, 552 (92.0%) cases were men and 48 (8.0%) were women. Mean age was 29.97 ± 10.40 years (range: 5–64 years). A significant difference was detected in gender distribution. Of the cases, 96.6% (n = 580) were Syrian war casualties. Lower extremity injury was the most frequently seen injury (n = 312; 52.0%). Mean MESS score was 4.71 ± 1.32 (range: 2-9). GCS score was
    Conclusion
    Young male and lower extremity injuries were most commonly encountered. Amputation was performed in the early period in cases with highest MESS scores. It was seen that amputation was common in crush injuries due to mine and blast. It was found that patient volume at emergency department and hospital and costs were increased due to war.
  • Asmat Ullah*, Abad Khan, Zafar Iqbal, Ismail Khan Page 649
    Background
    Substance abuse and its consequences are a matter of great concern in South-East Asian countries, especially Pakistan and Afghanistan. Due to contamination of Naswar with copper, or by any other physiological mechanism, there is a great chance of copper poisoning in addicts. Keeping in view the literature, there is no comparative study on serum copper levels (SCuL) in Naswar addicts. Therefore, it is very important to evaluate SCuL in this population.
    Methods
    The current study was performed in September 2016 where a total of 75 volunteers (selected from villages near the University of Peshawar, Pakistan) were grouped as Naswar addicts (n = 45) and the control group (n = 30). The addicts were compared to controls for age, weight, BMI, FBS and creatinine clearance. For serum analysis, about 3mL of blood was collected from which the serum was separated, digested, and then evaluated for SCuL using flame atomic absorption spectroscopy at the Department of Pharmacy and Centralized Resource Laboratory of University of Peshawar.
    Results
    The SCuL in addicts had a range of 2.6 to 11.1 µg/dL with a mean of 5.1 ± 2.4 µg/dL. In the healthy control group, SCuL was between 1.7 to 3.9 µg/dL with a mean of 2.6 ±0.1 µg/dL. The mean difference between the two study groups was statistically significant (P = 0.005); the duration of addiction and quantity of drug consumptions per day correlated positively with SCuL.
    Conclusion
    Serum level of copper in Naswar addicts is elevated compared to the Control group. The exact cause of SCuL elevations and the mechanisms involved must be studied in large group samples.
    Keywords: Addiction, Naswar, oxidative stress, Pakistan, poisoning, smokeless tobacco
  • Mona Malekzadeh, Sam Alahyari*, Saleh Sandoughdaran, Hanieh Zham Page 652
    Neuroendocrine tumors (NETs) are a rare and heterogeneous group of malignancies most commonly found in the gastrointestinal system. In this study, we examined the epidemiology of NETs in an Iranian population. The incident NET cases diagnosed between January 1, 2009 and December 31, 2014 were collected from databases of three hospitals in Tehran (Shoada-e-Tajrish Hospital, Imam Hossein Hospital and Pars Hospital). A total of 291 cases with NET diagnosis were identified. The most common NET location was gastrointestinal (71.4%), followed by Bronchopulmonary (7.2%) and Genitourinary (7.2%). The total number of identified NETs in our study increased from 25 cases in 2009 to 66 cases in 2014. In conclusion, our data suggests that the incidence of NETs is increasing slowly. Thus, etiologic studies for NETs are needed to help plan future preventive strategies.
    The authors declare no conflicts of interests
  • Ali Zare-Mirzaie, Mohammad Ahangarani Farahani, Gholamhossein Aghaei, Katayoun Ziari, Moeinadin Safavi* Page 655
  • Fereidoun Azizi, Atieh Amouzegar* Page 657