فهرست مطالب

Iranian Journal of health, Safety and environment
Volume:2 Issue: 3, Summer 2015

  • تاریخ انتشار: 1394/07/01
  • تعداد عناوین: 7
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  • Mohsen Janghorbani*, Masoumeh Faraji, Javad Ramazanpour, Reza Fadaei Pages 296-303
    The objective of this study was to assess the relative efficacy and tolerability of topical MJ1 compared to routine care in the treatment of histologically proven CL. A total of 150 patients with 297 lesions were randomly allocated to receive either topical MJ1 agent as a paste to applied to the lesions without cover three times a day for 20 days or routine care (intramuscular injection of meglumine antimonate 20 mg/kg/day for 2 weeks or intralesional 0.5-1CC for a total of four injection with one week interval). The primary end point of this study was the clinical cure of the lesion. Response to treatment was assessed at 1, 2, 3 and 8 weeks after start of therapy. Of the 132 lesions treated with MJ1, the mean size of lesions decreased from 423.9 to 30.4 mm2, 111 (84.1%) were reduced in size and 21 (15.9%) not responded. Correspondingly, in the 165 lesions treated with routine care, the mean size of lesions slightly increased from 295.8 to 330.5 mm2, 82 (49.7%) were reduced in size and 83 (50.3%) not responded. The differences were statistically significant (P<0.001). No sever adverse effect occurred. The findings highlight that topical treatment with MJ1 agent was much more effective than routine care and is safe and well tolerated.
    Keywords: Cutaneous Leishmaniasis, Meglumine Antimonate, MJ1 Agent, Iran
  • Seyed Ali Sajjadi, Mojtaba Afsharnia, Keykaous Azrah, Nasibeh Sargolzai Javan, Hamed Biglari* Pages 304-312
    Control of mutagenic and carcinogenic disinfection by-products, particularly Trihalomethanes (THMs) and Halo Acetic Acids (HAAs) in water treatment process is critical, due to their adverse effects on human health. Generally, reducing the toxicity of these by-products hinges on prior removal of the precursor materials, such as Humic Acid (HA) in drinking water. This study was conducted to investigate the role of some parameters that could affect the removal of HA, including HA (5 and 10 ppm) and H2O2 (20, 40, 60, and 80 ppm) initial concentrations, Iron (II), sulfate heptahydrate dosage (4, 8, 12, and 16 ppm), pH (2, 3, 4 and 5), Oxidation time (5, 10, 15 and 30 min), and Sunlight levels (322±13 kWm-2). To accelerate the process of HA removal, the Solar Photo-Fenton (SPF) process was employed by direct irradiation of converged sunlight in a Parabolic Trough Collectors (PTC), with 3m2 effective area. HA levels were measured via quantifying Dissolved Organic Carbon (DOC) concentrations by means of a TOC Analyzer method. The results showed that the SPF process is under control of the Fe & H2O2 ratio, the Fe2+ dosage and especially the pH quantity. In optimal condition, (pH: 4, oxidation time: 30min, initial HA levels: 50 ppm, H2O2 concentrations: 20 ppm Fe+2 levels: 4 ppm), the study found more than 98% DOC removal. In conclusion, the SPF, as an economically effective technique, could be applied for the removal of HA in aqueous environments.
    Keywords: Humic Acid, DOC, Sunlight, Solar Photo, Fenton Process, Hydrogen Peroxide
  • Somayeh Rafatbakhsh, Iran, Aref Salehzadeh*, Rasoul Yousefimashouf, Mohammad Najafimosleh, Zahra Karimitabar, Maryam Khedri Pages 313-319
    Microorganisms particularly bacteria presenting in insects such as Phlebotominae may play an important role in the epidemiology of human infectious disease. Nowadays, because of vector implications, the routine methods of controlling and spraying have no more beneficial effects on vectors and reservoirs. Little knows about the prevalence and diversity of sand fly bacteria. The main objective of this study was to determine the presence of bacteria of phlebotominae sand flies collected in Hamadan, west of Iran. This information is important in order to development of vector control strategies.The microbial flora of Phlebotomus papatasi and P. sergenti the main vector of Cutaneous Leishmaniasis in the old world, were investigated.We characterized 8 bacteria, including 5 Gram-negative bacteria: Acinetobacter lwoffii, Pseudomonas aeruginosa, Enterobacter cloacae, Edvardsiela sp. and Proteus mirabilis and Gram-positive bacteria: Bacillus subtilis, Staphylococcus saprophyticus and Micrococcus luteus.Our study provides some data on the microbiota diversity of field-collected sand flies for the first time in Hamadan. Our results indicate that there is a range of variation of aerobic bacteria inhabiting sand fly, which possibly reflect the ecological condition of the habitat where the fly breeds. Microbiota is increasingly regarded as an important factor for modulating vector competence in insect vectors. So, mirobiota can be effects on the biology of phlebotominae and their roles in the sandfly-Leishmania interaction.Further experiments are required to clearly delineate the vectorial role of sand flies. Because it is probable that in the future, factors such as environmental changes, migration and urbanization can ease the transmission of leishmaniasis in this area.
    Keywords: Bacteria, Iran, Leishmaniasis, Phlebotmine sand Flies
  • Somaieh Samani, Ramazan Mirzaei*, Ali Reza Ansari, Moghaddam Pages 320-324
    Considering the importance and essence of farmers’ health, this study has been conducted with the aim of evaluating the amount of the dust confronting farmers and the farmers’ respiratory symptoms and function during the course of wheat collection in 2014 in Zabul villages (Sistan & Balouchestan province, Iran).For this cross sectional study, the dust of the respiratory scope of two groups (farmers and non-farmers) was sampled by PVC filter for 90 minutes with the flow rate of 1.5 lit/min on the basis of NIOSH 0500 method during daily 8 work hours of 5 successive days of manual wheat reaping. Data regarding respiratory symptoms (n=50 rural men over the age of 40) was gathered through interviews and questionnaires, and pulmonary function was measured by Spiro lobe (made in MIR of the US); besides, data analysis was done by SPSS 18, T-Test, Chi-Square, and Logistic regression.The mean dust intensity confronting the farmers was 36.7 mg/m3, and the rate of some breathing complaints namely coughing (P≤0.001), sputum (P≤0.009) and shortness of breath (P≤0.026) became meaningful in the two groups. The average amounts of spirometer parameters of the farmers were less than that of the non-farmers, and the statistical difference of all the parameters except for FEV1/FVC (P=0.06) was meaningful (P≤0.05). The results of the present study indicated that confronting with dust could cause respiratory complaints and decrease spirometer parameters in the farmers.
    Keywords: Farmer, Dust, Respiratory capacity, Spirometer
  • Ahmad Reza Yazdanbakhsh, Hasti Daraei*, Masomeh Davoodabadi Pages 325-329
    Phenol is one of the serious pollutants from the chemical and petrochemical industries. This pollutant due to its convoluted structure is resistant to biodegradation. One of the methods that are useful to remove this pollutant is advanced oxidation (AOP).A laboratory scale study was done on a synthetic wastewater containing phenol. All experiments were done in batch conditions and effect of variables pH, amount of hydrogen peroxide, iron dosage, contact time and an initial concentration on the phenol removal were tested. The remaining phenol concentration was evaluated using the DR-5000 device. In order to effect of these parameters, the experiment was performance at pH 2 to 6, 5 to 45 ml/ml of peroxide, and time of 5 to 60 minutes with 2 to 15 g/ml iron (Fe˚).The optimum pH, the ratio of hydrogen, Fe˚and time were 3, 15 ml, 8g and 5 minutes respectively. Chemical oxygen demand (COD) index was chosen as the parameter for evaluation in this study. Result showed that mineralization of phenol was not complete. The COD removal efficiency was obtained 71%.According to the results of this study, Fenton-like process can be used for conversion organic resistant compounds to other compounds with lower toxicity.
    Keywords: Fenton, like, Advance Oxidation, Phenol, Iron Powder
  • Ayoub Ghanbary Sartang, Ehsanollah Habibi* Pages 330-334
    Along with widespread use of computers, work-related musculoskeletal disorders (MSDs) have become the most prevalent ergonomic problems in computer users. With evaluating musculoskeletal disorders among Computer Users can intervent a action to reduce musculoskeletal disorders carried out. The aim of the present study was to Assessment of Musculoskeletal Disorders among Computer Users in Isfahan University with Rapid Office Strain Assessment (ROSA) method and Nordic questionnaire. This cross-sectional study was conducted on 96 computer users in Isfahan university. The data were analyzed using correlation and line regression by test spss 20. and descriptive statistics and Anova test. Data collection tool was Nordic questionnaire and Rapid Office Strain Assessment method checklist. The results of Nordic questionnaire showed that prevalence of musculoskeletal disorders in computer users were in the shoulder (62.1%), neck (54.9%) and back (53.1%) respectively more than in other parts of the body. Based on the level of risk of ROSA were 19 individuals in an area of low risk, 50 individual area of notification and 27 individual in the area hazard and need for ergonomics interventions. Musculoskeletal disorders prevalence were in women more than men. Also Anova test showed that there is a direct and significant correlation between age and work experience with a final score ROSA (p<0.001). The study result showed that the prevalence of MSDs among computer users of Isfahan universities is pretty high and must ergonomic interventions such as computer workstation redesign, users educate about ergonomic principles computer with work, reduced working hours in computers with work, and elbows should be kept close to the body with the angle between 90 and 120 degrees to reduce musculoskeletal disorders carried out.
    Keywords: Musculoskeletal Disorders, Computer User, Rapid Office Strain Assessment, Nordic Questionnaire
  • Ghorbanali Mohammadi* Pages 335-340
    Although Musculoskeletal Disorders (MSDs) represents a common occupational problem, few epidemiological studies have investigated MSDs among industrial workers. MSDs are a common industrial health problem throughout the world and a serious cause of disability among the industrial workers.The goal of the study was to investigate the prevalence of musculoskeletal symptoms (ache, pain, or discomfort) among rubber workers in Iran, using the standard Cornell Musculoskeletal Discomfort Questionnaire (CMDQ). The study population consisted of 100 males with mean age 31.73. Out of every 10 workers, in the last work week, seven reported complaints in the lower legs. The results are also indicated age and experience were significantly associated with musculoskeletal symptoms in the different body regions.
    Keywords: Musculoskeletal Symptoms, CMDQ, Risk Factors, Rubber Industry