Resistance to Ciprofloxacin, Imipenem, Ceftriaxone and Cefotaxime in Culture Positive Samples of Pediatric Patients

The widespread use of antibiotics for prophylaxis or treatment of bacterial infections leading cause of resistance in bacteries. so recognition of this bacteries and bacterial resistance patterns is one of the most important factors in treatment of bacterial infections. it seems that due to widespread use of Ciprofloxacin, Imipenem, Ceftriaxone and Cefotaxime bacterial resistance for this antibiotics have been increased. So the present study was designed to determined antimicrobial resistance in bacteries that growth in culture of admitted patients in amirkola pediatric hospital. In this cross-sectional study between 1389-1390 all positive culture of patients sample was collected. Bacterial resistance pattern was determined by minimum inhibitory concentration according to CSLI-2006 protocol. All data has been analyzed by spss 18. The most frequent microorganism isolated in this study was E.cloi(68.7%), staph areus (6.1%), klebsiella, Shigella and staph saprophyticus(5.1%), streptococcus(4%), pseudomonas and entrobacter (3%). Based on the result of antimicrobial testing susceptibility to Ciprofloxacin, Imipenem, Ceftriaxone and Cefotaxime were 90.9%, 72.2%, 91.9% and 60.6%. E.coli had the most resistance rate to Ciprofloxacin (16.2%)and the most susceptibility rate to Cefotaxime(97.1%). Kellebsiela was susceptible to all antibiotics. In this study the most rate of susceptibility was seen in cefotaxime and the most rate of resistance was seen in ciprofloxacin.