Corneal Keloids and Keloid-like Lesions; Case Reports and Review of Literature

To report two cases of corneal keloid and keloid-like lesions and to present an overview of the literature.Case Reports: The first case was a 32-year-old female with past history of trauma to the right eye and subsequent surgery in childhood, who presented with a slowly growing smooth and whitish elevated corneal lesion. Histopathologic and immunohistochemical findings of the excised lesion were consistent with corneal keloid. The second case was a 19-year-old male patient who presented with had ontraumatic, bilateral, mildly elevated, paracentral and annular corneal opacities since childhood, which had aggravated in the past 5 years. Medical and family history was unremarkable. Confocal scan, impression cytology, histopathology and immunohistochemistry revealed evidence in favor of a primary keloid-like lesion. Corneal keloids are well-known lesions with characteristic clinicopathological features. “Keloidlike”is a general and nonspecific term that encompasses a wide range of entities. In primary and bilateral keloid-like lesions, especially in young adults, newly mutated corneal dystrophies that have not been yet defined should be considered.