Pyridoxine dependet seizure- A case report

Pyridoxine dependent seizure have been recognized as a rare and important cause of intractable seizure in neonates and infants. patient with this autosomal recessive disorder have recurrent seizures that are resistant to conventional anti convulsants but respond dramatically to intravenous or intermuscular administration of pyridoxine. The patient was 2 days old neonat who was refered to Amiralmomenin ali hospital because of recurrent seizures. all paraclinical studies were in normal ranges. the seizure was resistant to the conventional anti convulsant but after 100 mg of pyridoxine by intravenous injection it stopped dramatically.