P Wave Dispersion In Juvenile Idiopathic Arthritis Patients With Diastolic Dysfunction

Message:
Abstract:
0bjective: Juvenile idiopathic arthritis is the most common rheumatologic disorder of childhood. Cardiac involvement as pericarditis, myocarditis and valvular disease is common in Juvenile idiopathic arthritis. However, there are, few study concerning systolic and diastolic functions of the left ventricle in children with Juvenile idiopathic arthritis. P wave dispersion is a sign for the prediction of atrial fibrillation. A recent study found that rheumatoid arthritis patients had an abnormally high P wave duration and P wave dispersion, markers for supraventricular arrhythmogenicity. In this study, we aimed to evaluate P wave dispersion and its relation with diastolic dysfunction of the left ventricle in patients with Juvenile idiopathic arthritis.
Methods
We performed electrocardiography and Doppler echocardiography on patients and controls. Maximum and minimum P wave duration were obtained from electrocardiographic measurements. P wave dispersion defined as the difference between maximum and minimum P wave duration was also calculated.
Findings
No statistically significant differences were found between the patients and controls in minimum, maximum P wave duration and P wave dispersion. Among the diastolic parameters in patients group, increased late flow velocity, decreased early flow velocity and prolonged isovolumic relaxation time reflected diastolic dysfunction.
Conclusion
During 12 months of follow-up, no supraventricular arrhythmias were documented in Juvenile idiopathic arthritis with diastolic dysfunction. Juvenile idiopathic arthritis with diastolic dysfunction has normal atrial conduction parameters and therefore seemingly do not have an increased risk of atrial fibrillation.
Language:
English
Published:
Iranian Journal of Pediatrics, Volume:22 Issue: 4, 2012
Page:
512
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