The Effect of Coriander Seed Powder Consumption on Atherosclerotic and Cardioprotective Indices of type 2 Diabetic Patients

The purpose of this study was to investigate the effect of coriander seed powder (CSP) on the atherosclerotic and cardioprotective indices in type 2 diabetic patients. In this study, fifty type 2 diabetic patients consumed 2 capsules of the CSP /day for a period of 6weeks. Blood samples were collected from the patients before and after the course of CSP consumption after 12 h of fasting. The plasma glucose, total cholesterol, triglyceride, LDL-C, HDL-C, urea and creatinine were measured before and after the CSP consumption for 6 weeks. Atherosclerotic and cardioprotective indices were calculated. The CSP consumption for 6 weeks in type 2 diabetic patients significantly reduced plasma glucose, total cholesterol, triglyceride, and LDL-C (p< 0.001), but HDL-C was not significantly changed (p≥ 0.05).But there was no significant effect on urea and creatinine concentrations. Atherosclerotic index decreased while cardioprotective indices increased. Since the CSP consumption reduced several components of metabolic syndrome and decreased atherosclerotic and increased cardioprotective indices, the CSP may have cardiovascular protective effect in type 2 diabetic patients.