Study of bacteria causing skin infections and antibiotic resistance in patients referred to Shohada and Loghman hospitals

Diagnosis of bacterial causes of cutaneous infections and determination of their resistance to different antibiotics is required for choosing the optimal treatment. This study was performed on bacterial cultures which were taken from patients with cutaneous infections. Samples were collected from 110 patients with cutaneous infections referred to the clinical laboratories in Shohada and Loghman in 1388-1389. The samples were cultured by routine microbiological methods for isolation of microbial agents. The antibiogram disc agar diffusion technique was used to evaluate the sensitivity of microbial agents to antibiotics. The bacteria causing cutaneous infection in the order of their prevalence included Staphylococcus aureus (31%), Escherichia coli (22%), coagulase-negative Staphylococci (12%), Streptococcus spp (8%), Enterobacter (8%), Klebsiella (5%), Acinetobacter (5%), Pseudomonas spp (4%), Enterococcus (3%) and Proteus (2%). The most resistance organisms were Acinetobacter (86%), Enterobacter (81.7%), Enterococcus (78.4%), and the most sensitive organisms were Proteus (61.1%) and Streptococcus spp (60.7%). Staphylococcus aureus is the most common microbial agents of cutaneous infections. In order to prevent bacterial resistance to antibiotics we must prescribe antibiotics based on bacterial culture and antibiograms.