Epidemiology of urinary tract infection and antibiotic resistance pattern of E. coli in patients referred to Imam Ali hospital in Farokhshahr, Chaharmahal va Bakhtiari, Iran

Urinary tract infection (UTI) is one of the most common nosocomial infections. Antibiotic resistance patterns vary in different regions. The aim of this study was to determine the prevalence of bacterial agents causing UTI and antibiotic resistance pattern of E. coli in outpatients referred to the Imam Ali Hospital of Farokhshahr. In this descriptive-analytical study، 848 urine samples were examined during a five-month period. After the separation of infection agents، the test of sensitivity to antibiotic was performed according to Clinical and Laboratory Standards Institute (CLSI) method. The urine test result was positive in 74 (8. 72%) patients of 848 eligible ones. The most common isolated bacteria were E. coli and Staphylococcus; 52 (70. 27%) and 15 (20. 27%)، respectively. 34 (65. 38%) were female and 18 (34. 62%) were male from 52 patients infected with E. coli. Based on the results of antimicrobial resistance test، the highest resistance was with ampicilin (85. 71%)، nalidixic acid (78. 78%)، and ciprofloxacin (46. 51%). Furthermore، the highest sensitivities belonged to nitrofurantoin (92. 30%)، amikacin (66. 67%) and gentamicin (62. 50%)، respectively. Most cases of infection were in over 47 years. The highest sensitivity was to nitrofurantoin and the highest resistance was to ampicilin. According to the UTI، data obtained from experimental treatment with antibiotics، ampicilin is not appropriate in most patients with UTI.