Effect of Regular Aerobic Training On Resistin Gene Expression In Active Young Females

Resistin is an adipocyte-derived hormone، plays a key role in regulating energy homeostasis and metabolism. The aim of this study was the effects of regular aerobic training on resistin gene expression in trained young Female. 20 females were randomly divided into control and experimental group. The experimental group performed aerobic training for 8 weeks، 4 sessions in every week، and with the intensity of 70-80 % of maximum heart rate. The control group did not do any train in this period. Resistin expression was investigated after separating the lymphocytes by centrifuge and using semi-quantitative RT-PCR. Statistical analysis was performed by independent and paired t-tests. Results of this study showed that there were significant different between the average of BMI and the fat percentage before and after the 8 weeks in experimental group (p=0/00). There were significant difference between the average of resistin gene expression related to the post-test in control and experimental group (p=0/036، t (18) = -2/268). Overall، eight weeks regular aerobic exercise through reduction of weight، body fat and elevation of resistin gene expression cause reduction of the possibility of cardiovascular diseases and increase of strenghth anti-oxidation defences of the body، in young female.