Effect of Aerobic training on serum chemerin levels and lipids of plamsa in overweight women

Chemerin is a novel adipokine that play an important role in regulating lipid metabolism and adipogenesis. There is limited information available regarding the effect of exercise training on serum chemerin concentrations. The purpose of this study was to investigate the effect of Aerobic training on serum chemerin levels and lipids of plamsa in overweight women. 20 Overweight subjects (age: 35. 64±5. 55 yr، weight: 69. 62±9. 30 kg، body mass index: 27. 93±3 kg/m2) were randomly assigned to aerobic training (n= 12) and control (n= 8) groups. Aerobic training was performed 4 times weekly for 8 weeks. Resting levels of plasma chemerin and lipid profiles were measured before and after the intervention. After 8 week aerobic training، levels of chemerin plasma were significantly decreased in aerobic trained group when compared with their control groups (p<0. 05). Concurrently، levels of HDL-c were significantly decreased (p<0. 05) whereas، levels of cholesterol، TG and LDL-c، showed no significant changes (p> 0. 05). No significant correlations between chemerin levels and weight loss were observed in subjects with overweight women. The present study demonstrated، 8 weeks aerobic training، reduced serum chemerin concentrations in overweight women. Whereas، aerobic training exercise programmes affected the lipid profile response of obese subjects differently. However further research is warranted in order to unravel the molecular mechanism for the range of responses and the role of serum chemerin.