Survey of the efficacy of antibiotic therapy on complications consequent of tonsillectomy and adenotonsillectomy

Tonsillectomy and adenotonsillectomy are the most common ENT surgeries. Because there are not sufficient investigations about antibiotic therapy، and، also، due to. some disagreement over post-surgery use of antibiotics، the present study was designed to find out the efficacy of antibiotic therapy on consequent complications of tonsillectomy and adenotonsillectomy. This randomized، clinical trial (RCT) study was carried out on 138 candidates for tonsillectomy or adenotonsillectomy. The patients were randomly divided into two equal groups; the firstgroup، i. e. the cases، received antibiotics and the. Control group received no antibiotics. Both groups were compared regarding variables such as fever، mean number of the white blood cells، severity of pain and” nausea and vomiting” after operation، vocalization، mean lapse in drinking time، extent of bleeding during and after operation، pus secretion، regenerating of injury after the two types of surgery. The obtained data was analyzed by means of SPSS software (version 13). using chi square، T-test، Fisher and Man-Withny tests at the significant level α<0. 05. It was found that 49. 3% of the cases and 40. 6% of the controls were males and the rest females. Mean and standard deviation of the age was 12. 2±8. 3 and 11. 5±5. 9 in case and control groups، respectively. Mean and standard deviation of severity of the pain and “nausea and vomiting” were 2. 72±0. 95 and 16. 4±0. 94، and 2. 54±0. 83 and 16. 3±1. 4 in the cases and controls 24 hours after surgery was 12923±3544 and 14223±3591، respectively. Only، mean number of the white blood cells difference was significantly higher in the control group (14223±3591 vs، 12923±3544، P=0. 03). Administering antibiotics to tonsillectomy and adenotonsillectomy patients has no effect on complications consequent to these surgeries.