The Association between Celiac Disease and Ulcerative Colitis

Background and Celiac disease (CD) is a genetic disorder that causes inflammation in the lining of the small intestine. Recent literature has shown a relation between inflammatory bowel disease and celiac disease. This study aimed at determining the prevalence of celiac disease in patients with ulcerative colitis (UC). In this cross-sectional study 84 patients (aged 17-79 years of old) with UC underwent screening test for CD. Anti TTG Ab and Total IgA Ab were checked for all patients. The mean age of the patients was 39.26±13.29 years. In all cases Anti TTG and Total IgA Ab were negative. In this study we found no association between CD and UC. However, more studies with larger sample size are recommended to find the exact relation between these diseases.