Breast Sarcoma: A Review Article

Breast cancer is the most common malignancy in women and it is also the leading cause of cancer death in women worldwide. The incidence of this disease is increasing particularly among women aged 50-64. It is the most common malignancy among Iranian women over the past decades and it is spreading rapidly. Sarcoma of the breast is rare. It can occur primary or secondary way. Primary sarcoma’s occurrence in breast is extremely rare and is a highly aggressive tumor. 5. 7% of the primary breast sarcomas are Angiosarcoma. Secondary sarcoma is developed after breast irradiation for a previous breast carcinoma، associated with poor prognosis. Angiosarcoma is 56. 8% of all breast sarcomas. The main diagnosis of breast Sarcoma is fine needle aspiration (FNA). Imaging can also be helpful. Course mammography in breast sarcoma is nonspecific but as a better method of ultrasonic mammography in detecting breast sarcoma it is proposed to treat breast sarcoma total mastectomy is the most common procedure in which the entire breast is removed، but the lymph nodesare notremoved. An adequate resection margin is the single most important determinant of long-term survival with breast sarcomas. As with soft tissue sarcomas arising elsewhere in the body، the prognosis for breast sarcomas is highly dependent upon histologic grade and tumor size.