Changes in FABP5 Plasma Levels after a Period of Aerobic Exercise with Increasing Intensity in Women with a Normal Weight and Overweight

Introduction and

Disturbances in adipocyte lipolysis in obesity may contribute to elevated circulating fatty acids concentrations. Fatty acids metabolism is influenced by epidermal lipid binding protein (FABP5/ mal1). The aim of present study was to investigate the effect of 8 week aerobic training on plasma levels of FABP5 in women with different body mass index.

Thirteen normal weight health women (BMI<24. 9 kg/m2، mean age ± SD، 31. 08 ± 1. 8 years) and twelve overweight women (BMI>25 kg/m2، mean age ± SD، 32. 3 ± 1. 8 years) participated in this study. The aerobic training program was carried out for 8 weeks، 3 sessions per week at 40-80% of maximal reserved heart rate. Duration of each session was 25 minutes in the first week and it increased up to 45 minutes in the 8th week of exercise. Plasma levels of FABP5، lipid profile such as HDL، LDL، Cholesterol، triglyceride and body composition index before and 48h after the training period were measured.

Results of t-test showed that eight weeks of aerobic exercise had no significant effect on plasma levels of FABP5، weight and body mass index. Cholesterol levels in both group and LDL levels in normal weight group was increased significantly (P<0. 05). Whereas changes in HDL and triglycerides in the two groups was not significant compared to before exercise.

The results of this study showed that 8 weeks of aerobic exercise with increasing intensity does not effect on changes of plasma FABP5 in women with a normal weight or overweight.