The effect of 12 week vitamin E supplementation and regular physical activity on selected liver enzymes of non-alcoholic fatty liver patients

The purpose of this research was to evaluate the effects of 12 week vitamin E supplementation and regular physical activity on level of liver enzymes in non-alcoholic fatty liver patients. Thirty patients suffering from non-alcoholic fatty liver participated in this research voluntarily. They were randomly divided into two groups: Group A (patients who use two 400 mg vitamin E tablet daily in the morning and at night for 12 weeks، n=10)، and group B (patients who received programmed regular physical exercise، n=10). Aspartate amino transferase (AST)، Alanine amino transferase (ALT)، and alkalin phosphatase (ALP) Enzymes were measured. Sonography was used to measure fatty steatosis grade. In sonography، although there was no significant difference in fatty steatosis grade between groups (p>0. 05)، there was significant decrease after treatment in both groups compared with pre-treatment (p<0. 05). All liver enzymes were decreased in both groups after treatment compared with pre-treatment (p<0. 05). There was no significant differences between groups (p>0. 05). It seems that regular physical activity without considering the kind of diet or weight loss results in decreasing liver enzymes and ultrasound evidences in non-alcoholic fatty liver patients. According to side-effects of long duration supplementation of vitamin E، regular physical activity can be more suitable method to treat non-alcoholic fatty liver.