Efficacy of antibiotic therapy on pains consequent of tonsillectomy and adenotonsillectomy in a randomized clinical trial study

Pain is the most important complication following tonsillectomy and pharyngeal palatine tonsil, and coupled palatine tonsils and throat. There isno enough investigation about antibiotic therapy on this complication. Furthermore, as there is no agreement in the use of antibiotic on pain complication, this investigation designed for finding of the efficacy of antibiotic therapy on pain complication consequent of tonsillectomy and adenotonsillectomy and its severity. Method and Materials: This randomized clinical trial (RCT) study was carried out on 138 patients who were candidate for tonsillectomy or adenotonsillectomy. The patients according to systematic randomized divided into two equal groups; the first group as the intervention, received antibiotic and the other as the comparison received no antibiotic. Both the groups were compared in the variables such as: throat and ear pains, their severity, and patient's need to analgesic drugs after tonsillectomy and adenotonsillectomy. Data were analyzed by SPSS software version 13 and using chi-square, Fisher and Man-Withny tests and α<0.05 considered significant statically. Our finding showed that the mean and standard deviation of severity of the pain were 2.72 ± 0.95 and 2.54 ± 0.83 in intervention and comparison groups respectively and in comparing there is no observed significant difference (p= 0.29). In comparing the other of all variables there is no observed significant difference statically. Considering the results originated from our study it may be concluded that the use of antibiotic or not using, has no effect on the pain complication and its severity consequent of the tonsillectomy and adenotonsillectomy.