The effect of high intensity interval exercises in hypoxia normobaric and normoxia conditions on serum interleukin-6 and its relation with glucose in non-athlete young men

The purpose of this study was to determine the effect of high intensity interval exercise in hypoxia and normoxia conditions on serum interleukin-6 (IL-6) response and its relation with glucose in non-athlete young men. 9 sedentary volunteers، with age 24. 6±0. 5 yr.، weight 72. 9±4. 9 kg and height 174. 8±5. 3 cm participated in this study. Subjects'' main activity for 30 min including 10 times 1-min with 80% Wmax on cycle ergometer in hypoxia normobaric condition (15. 3 to 15. 5 % of oxygen of 2500 m high) and after a week in normoxia condition (20 to 21% of oxygen) were performed. Between each of the repetitions to return to the initial state، the intensity of the activity was reduced to 50% Wmax. In the test session، to measure IL-6 levels and glucose، 2 ml of blood each at different times (before، immediately after and two hours after the activity)، subjects were collected from the brachial vein. To analyze the data، analysis of variance with repeated measures was used. Serum levels of IL-6 subjects immediately and two hours of activity in hypoxic conditions and Normoksy showed decreased insignificantly (P>0. 05). The correlation between IL-6 levels and glucose were observed between the two conditions (P>0. 05). Based on the results we can say that the implementation of the periodic activity of severe dysfunction of the immune system in young male athletes are not created. However، due to the influence of intensity، duration، type of activity and the degree of hypoxia on the immune response، it is better to provide intense sporting activities for young people more closely to non-athletes.