Evaluation of hyperlipidemia in different types of coronary involvements needing bypass surgery

Acknowledgement: Our deepest regards goes toopen heart surgery department of ghaem hospital colleagues, Surgical Oncology Research Center and Surgical endoscopic research center whom without their sincere help this study could not be performed. hyperlipidemia is one of the major risk factors for coronary artery disease and progression of atherosclerosis. Severity of coronary artery stenosis and the extent of arterial involvement are important indicators in therapeutic planings. In this study we have evaluated the relation between increases in different serum lipids and the number of involved coronary arteries among candidates of coronary artery bypass. Method and materials: A total of 150 patients who underwent coronary artery bypass in open heart surgery department of Qhaem hospital were divided into three groups of single vessel, two vessels and three vessels involvement according to angiographic findings. Then lipid profile and prevalence of different hyperlipidemias were compared between these three groups. among our cases, single vessel disease was reported in 2.7%, two vessels disease was reported in 26% and three vessels disease was reported in 71.3%. Male to female ratio was 86 to 64. like other studies, prevalence of coronary artery disease was higher in male gender. Mean age was 58.2 years in our study. All groups were almost similar in age, sex and prevalence of MI and history of smoking. Comparing different types of hyper lipidemia between three groups, based on the number of involved coronary arteries, prevalence of total cholesterol and LDL hyper lipidemia were significantly higher in multi vessel disease. Total serum cholesterol and LDL level were important prognostic factors and indicators for prediction of extent of coronary artery disease.