Leukemia-induced Gingival Overgrowth as an Early Manifestation in Pregnancy: A Case Report

Leukemia is a neoplastic disease with early oral and periodontal manifestations such as ulceration, infection, bleeding and gingival hyperplasia. This paper describes a 39-year-old pregnant woman with a diagnosis of acute myelomonocytic leu-kemia (AML), with gingival enlargement in the upper and lower jaws. A gingival biopsy was performed, followed by a complete blood count and peripheral blood smear. From a histopathological view, infiltration of the neoplastic (myelomo-nocytoblastic) cells was observed and many immature lymphoid cells were revealed by the hematologic tests. The interest-ing clinical finding about this case was the absence of spontaneous bleeding and profuse bleeding on probing. This case is reported to emphasize the leukemia-induced gingival enlargement in pregnancy and the early diagnosis of AML by dentists, which results in immediate treatment and management of the patient.