Effect of Standardized Polyherbal Formulations on Blood Glucose Body Weight Food and Water Consumption of Rats
Author(s):
Abstract:
Standardization of polyherbal formulation is mandatory to evaluate the best quality of drugs for therapeutic value. The main objective of this study was to develop a standardized, safe and effective polyherbal juice with significant anti-oxidant and anti-diabetic activity.
Methods
Polyherbal juice was formulated using cold maceration method and was evaluated for Total phenolic content, Total flavonoid content, Antioxidant activity, Particle size, IR, HPTLC and Heavy metal analysis. Results
Total phenolic content was found to be 139.23 ± 0.072 mg/g gallic acid equivalent and Total flavonoid content was 62.01± 0.063 mg/g Catechin equivalent. In DPPH scavenging assay the RC50 value of polyherbal formulation was found to be 6.0 µg/ml. Preliminary phytochemical tests and HPTLC was performed for Quantitative Analysis of Phytoconstituents in formulation. Conclusion
In-vivo study shows significant anti-diabetic activity as compared with marketed formulations. Thus polyherbal formulation possesses good anti-diabetic and antioxidant activity.Keywords:
Polyherbal juice , DPPH , Standardization , Anti , oxidant , Anti , diabetic
Language:
English
Published:
Pharmaceutical Sciences, Volume:21 Issue: 2, Sep 2015
Pages:
57 to 64
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