The Protective Effect of Vitamin E on Spermatogenesis indexes in Rats Treated with Bisphenol A
Author(s):
Abstract:
Aim: The aim of this study was to investigate the preventive role of vitaminE (Vit.E) on spermatogenesis indexes in rats following exposure to Bisphenol A.
Materialand and
Materialand and
Methods
Adult male wistar rats with the mean body weight of 231±10g were randomly divided into 4 groups (n=6): control, BPA (250mg/kg/day), Vit.E (150mg/kg/day) and BPA Vit.E. Oral treatment was performed three times a week till 56 days. At the end of the treatment, the rats were killed and their left testis were weighed, fixed and stained using Heidenhain's Azan methed. Histological and morphometrical analysis of spermatogenesis was carried out. Data were analyzed using One Way ANOVA and the means were considered significantly different at pResults
Testis weight (PConclusion
Vitamin E can compensate for the undesired effects of BPA on spermatogenesis and therefore could be considered as a therapeutic supplement in the case of BPA toxicity.Language:
Persian
Published:
Journal of Cell &Tissue, Volume:7 Issue: 1, 2016
Page:
81
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