Clinical comparison of coronally advanced flap combined with amniotic membrane or subepithelial connective tissue in treatment of Miller's class I and II gingival recessions: a split mouth study

The aim of the present study was to compare coronally advanced flap (CAF) with amniotic membrane to CAF with connective tissue graft (CTG) in the treatment of Miller’s class I&II gingival recessions.
11 systemically healthy patients, with 30 Miller’s class І and ІІ gingival recessions ≥3 mm, were selected and randomly divided into two equal groups. Gingival recessions in the control group were treated with coronally advanced flap and CTG, and in the test group with CAF and amniotic membrane. The clinical parameters including: probing depth (PD), clinical attachment level (CAL), recession depth (RD), recession width (RW), and keratinized tissue width (WKT) were measured at baseline, 1, 3, and 6 months postoperative. A P value RD, RW, CAL, and MGJ position changed significantly between baseline and 1 month postoperatively (p The findings of the present study demonstrated that although use of amniotic membrane resulted in decreasing surgical time and patient morbidity, but superior results were achieved by using CTG.