Laboratory Comparison of Remineralization Rate of Fluoridated GC Tooth Mousse with Concomitant Use of Fluoride Mouth Wash and GC Tooth Mousse on Enamel of Primary Tooth

Currently, a substance called casein phosphopeptide-amorphous calcium phosphate has been used as a substitute for fluoride mouthwash. This study aimed to compare the remineralization rate of fluoridated GC tooth mousse with concomitant use of fluoride mouthwash and GC tooth mousse on demineralized enamel lesions.
In this laboratory study, 50 samples were selected from 30 intact human premolars, halved into buccal and lingual segments, and randomly divided into five groups. Enamel health was recorded using a DIAGNOdent device and Vickers microhardness test.
Afterwards, the remineralized agents were applied to the surface of samples for two weeks as follows: 1) Control, 2) Fluoridated GC tooth mousse, 3) GC tooth mousse, 4) Sodium fluoride mouthwash and 5) Sodium fluoride mouthwash GC tooth mousse. Repeatedly, enamel remineralization values were recorded via DIAGNOdent device, and data were analyzed using one-way and two-way repeated measures ANOVA tests.
Our findings indicated that no significant difference was observed between remineralization rate of fluoridated GC tooth mousse and concomitant use of fluoride mouthwash and GC tooth mousse, evaluated by DIAGNOdent device (P=0.959) and Vickers microhardness test (P=0.884).
According to the results, application of fluoridated GC tooth mousse with concomitant use of fluoride mouthwash and GC tooth mousse had a similar impact on remineralization of demineralized enamel lesions.