Incidence and Risk Factors of Oral Mucositis in Patients with Breast Cancer Who Receiving Chemotherapy in Al-Bashir Hospital

Abstract:
Background
Oral Mucositis (OM) remains the most common side effect of chemotherapy affects negatively on patient's quality of life.
Subjects and
Methods
Convenience samples of patients who received chemotherapy were followed from first or second cycle of chemotherapy until OM occurrence. We reviewed 75 female patients with breast cancer who received chemotherapy with mean age (47.2 SD ± 8.62861). We used WHO scale to assess the severity of OM. Demographic and other variables (age, number of cycle before appearance of signs of OM, WBC count, neutropenia count, creatinine and BMI) were filled in questionnaire.
Results
81.3% of reviewed patients were suffering from OM and (52.4%) of them were shown score 2 according to WHO classification, Taxane included chemotherapy protocol was the only significant variable that associated with OM occurrence (p=0.009).
Conclusion
In this study; Taxane is the only risk factor that significantly associated with occurrence of OM.
Language:
English
Published:
International Journal of Hematology-Oncology and Stem Cell Research, Volume:10 Issue: 4, Oct 2016
Pages:
217 to 223
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