Relationship between Cholesterol, HDL, LDL and Toxoplasmosis Infection

Toxoplasmosis is an important infection which is caused by Toxoplasma Gondi. This protozoa infection is prevalent among many warm-blooded animals and spreads worldwide. Toxoplasmosis could lead to still birth in pregnant woman and death in immune deficiency cases. The purposes of this study were determination of serum Cholesterol, HDL and LDL in patients infected with toxoplasmosis.
In this descriptive and analytical – cross sectional study, 200 persons who referred to Farabi laboratory (Ardabil) during summer and fall 2014, were examined. After preparation of blood sample and serum, Electro chemiluminescence(ECL) technique was used to detect contamination of toxoplasmosis and in order to determination of the serum levels of Cholesterol, HDL and LDL lipids, it was applied Auto analyzer technique. Finally data was analyzed through SPSS19 using independent t-test method.
From 200 studied cases (150 women and 50 men), 22 cases (14 women and 8 men) were positive for toxoplasmosis (Anti-toxoplasmosis Ig G were above 30). Cholesterol, HDL and LDL lipids were measured in both case (22 infected cases) and control (22 non-infected persons) groups. The mean of Cholesterol, HDL and LDL were 147.27, 32.23, 95.63 in control group and 173.59, 49.32 and 94.91 in case group respectively.
The amount of Cholesterol and HDL in case group (Toxoplasmosis positive) were higher than control group (Cholesterol Sig. = 0.016 and HDL Sig. = 0.001), whereas the amount of LDL had no significant difference between these two groups (LDL Sig. = 0.92).