The Role of Aerobic Training and Omega-3 Supplement Intake on Phosphorylated Tau Protein in the Hippocampus of Alzheimer Induced Rats with Homocysteine
Author(s):
Abstract:
The aim of this study was to assess the impact of eight weeks aerobic training and omega-3 supplement intake on phosphorylated Tau protein in the hippocampus of Alzheimer induced rats with homocysteine. For this purpose, 60 Wistar male rats (twelve-weeks-old and weight 222.31±11.91 g), divided into six groups, including: Alzheimers rat Omega-3, Alzheimers rat training, Alzheimers rat training Omega-3, healthy control rat, control sham and Alzheimers control rat. Alzheimer's disease induced by injection of homocysteine (60mM) into the rat brain ventricle. Training with a speed of 20 m/min (60 minutes at each session and five days a week on the treadmill) was applied. The supplement group, was received Omega-3 supplement 800mg/kg of body weight, daily for eight weeks. Level of phosphorylated tau protein measured using ELISA method. In data analysis, a one-way analysis of variance and Tukey test as a post hoc, were used )P
Language:
Persian
Published:
Sport Physiology, Volume:8 Issue: 31, 2016
Page:
171
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