Frequency of Cytomegalovirus Active Infection in Renal Transplant Recipients in Kermanshah by ELISA and Real-Time PCR methods

Cytomegalovirus (CMV) is one of the most important infections in renal transplant recipients. This virus is a major cause of death in these patients. In this study, we investigated Frequency of Cytomegalovirus active infection in renal transplant recipients in Kermanshah by ELISA and Real-time PCR methods, 2013-2014.
This research was a descriptive cross-sectional study. 142 renal transplant recipients were investigated in this study during 2013-2014. Demographic information of patients was recorded. The clinical samples of patients were investigated as presence of IgG, IgM and Cytomegalovirus DNA by ELISA and Real-Time PCR methods. The results analyzed by SPSS software version 20.
Results of this study showed, of 142 patients, 93 cases (65.5%) were male. The mean age of patients was 47.61±29.43. 130 cases (91.5%) and 53 cases (37.3%) were positive as IgG and IgM, respectively. Cytomegalovirus DNA were seen in 51cases (35.9%). There in not the meaningful relation between age, gender with Cytomegalovirus active infection (p>0.05).
Results of this study showed the frequency rate of Cytomegalovirus active infection in renal transplant recipients in Kermanshah is high and these active infections are detectable using Real-Time PCR method with more rapid and accurate.