Pathological patterns of endometrial curettage samples in women referred with abnormal uterine bleeding: A descriptive study

Abnormal uterine bleeding (AUB) is among the most complex gynecological problems, especially during the middle and old age. The aim of this study was to assess the pathological findings in endometrial curettage samples of abnormal uterine bleeding and the risk factors associated with them.
In our cross-sectional study, we included all the referring women with AUB complaint to Birjand’s Vali-e-Asr hospital gynecology clinic from August 2014 to February 2014. The data were collected via interviews and dilatation and curettage (D&C) pathologically evaluated.
A total of 152 patients were enrolled. The mean age of participants was 44.09 years. The most common manifestations were menorrhagia, metrorrhagia, and menometrorrhagia with frequencies of 66 (43.4%), 53 (34.9%), and 160 (10.5%), respectively. The most frequent pathological findings were normal pattern (51.7%, n=78), polyps and abnormal endometrial proliferation (29.1%, n=44), and hyperplasia (14.6%, n=22). No significant association was found between the pathologic results and age, bleeding on admission, number of pregnancies, contraception procedure, occupation, history of endometrial hyperplasia, history of ovarian cysts, hypothyroidism, hyperthyroidism, hyperprolactinemia, hypertension, and diabetes.
Overall, the most common causes of AUB involve non-organic causes, that is, natural causes although curettage is still an acceptable method for assessment of AUB, given the importance of AUB in diagnosis of endometrial cancers in women over 40 years old.