Determination of ABO/Rh blood group, sex and age with severity of Helicobacter pylori infection in Iranian gastrointestinal patients

Helicobacter pylori infection currently become as an endemic worldwide health issue. The infection causes variety of gastrointestinal diseases. The role of blood groups is established in body’s response to microorganisms and the development of gastrointestinal disorders. This study aimed to investigate the relationship between blood groups, age and gender of Iranian population and the severity of infection with this bacteria.
The study included 160 patients with dyspepsia symptoms referred to Hajar hospital in Shahrekord. Biopsy specimens were investigated in terms of being infected with H. pylori by using PCR for 16SRNA gene and glmM gene and blood groups of patients were determined by using hemagglutination routine test.
Results and It was observed that 61.87% of patients were positive in terms of bacteria existence and 61 of them were negative. 62.26% of infected patients with bacteria were female. The highest frequency of ABO blood groups among infected patients, belongs to O blood group with 40.66 percent (P>0.05). H. pylori was found in 77.12% of Rh patients (P 0.05). The severity of this bacterial disease were observed in patients with blood group O more than others (P