New Strategy for Determination of Levodopa using Carbon Paste Electrode Modified with SiO2@Fe3O4/GR Nanocomposite, Ionic Liquid and ferrocenylethylnyl(fluoren-9-one)-2

In this study, SiO2@Fe3O4/GR nanocomposite, ionic liguid and 2(ferrocenylethynyl)fluoren-9-one (2FE) modified carbon paste electrode (SiO2@Fe3O4/GR/2FE/IL/CPE) was used for the determination of levodopa. The electrochemical behavior of levodopa was investigated using cyclic voltammetry (CV), chronoamperometry (CHA) and differential pulse voltammetry (DPV) techniques. Due to the fine characteristics of modified electrode, a good linear relationship between the anodic peak current and levodopa concentration in the range 0.1–500.0 μM was observed. The detection limit (3σ) obtained by DPV was 6.0×10-8 M (S/N=3). Here, a new sensor is introduced that is simple, rapid, sensitive, selective and cost-effective for quantitation of levodopa in real samples.