Symptoms and Signs in Patients with Brucellosis in Iran: a Systematic Review

Despite progress in health and medical sciences in the recent decades, human brucellosis (Malta fever) is still an important endemic disease in IR of Iran. Various signs and symptoms of the disease in patients makes the diagnosis of the disease difficult. Knowing the frequency of these signs and symptoms in the patients through the country can improve the level of awareness of the them and give a measure of the overall assessment of the disease.
This study was a systematic review on studies conducted in IR of Iran and reported the frequency of signs and symptoms of brucellosis. Finding the studies was done by using the broad keywords in the intended database such as Cochrane, Campbell Collaboration, Pubmed, Sciencedirect, SID, and Magiran.
Defining the principles of inclusion and exclusion criteria through 881 found articles, 23 articles were analyzed. The most common signs and symptoms were fever (67.46%), arthralgia (59.22%), sweating (56.96%), fatigue or weakness (54.03%) and back pain (51.21%).
Brucellosis is a disease with a Thousand Faces and can cause various kinds of clinical signs and symptoms in patients. Recognizing these signs and symptoms and awareness of diversity and frequency of each of them can make diagnostic process shorter and easier.