Effect of Cycloplegia with Cyclopentolate 1% on Corneal Parameter and Refractive State of the Eye

To determine refractive state and corneal parameter changes after cycloplegia with cyclopentolate 1% using dual scheimpfluge imaging system.
Healthy volunteers between the ages of 10 and 40 years who were referred for ophthalmic evaluation in a 3-month period were included. Complete ophthalmic examination, auto-refraction and corneal imaging with the Gallilei dual scheimpfluge system was performed before and after 30 minutes of applying 1% cyclopentolate. Changes in refractive and corneal parameters were evaluated.
One hundred and six patients with mean age of 28±5 years or 212 eyes (201 myopic and 11 hyperopic) were evaluated. The mean spherical equivalent before cycloplegia was -3.4 ± 2.6 D (diopter), after cycloplegia the mean hyperopic shift was 0.4±0.5 D (P The refractive state, posterior corneal curvature and corneal thickness changed statistically and significantly after cycloplegia, so it is recommended not to measure these parameters in cycloplegic state for clinical judgment, in IOL power calculation and refractive surgery.