Review of antibiotic resistance of Helicobacter pylori in Iran and the world

Helicobacter pylori has infected almost half of people around the world . The annual incidence of helicobacter pylori infection is 4-15% and 0.5% in developing and developed countriesrespectively. The aim of this study was to review antibiotic resistance of this organism in Iran and other parts of the world.
In this study Pubmed, (SID),ISI, Embase, Google scholar and Scopus databases were searched. In this study 20 Iranian, 8 Asian, 3African, 2 American and 17 European articles have been selected and reviewed. Studies had been selected in the period 1994 -2014.
Iranian studies reported very high resistance against metronidazole (57. 4%), which is roughly consistent with the results of other Asian countries (46. 6%). The average resistance was lower in Iranian in comparison with African countries (97. 55%). The mean ciprofloxacin resistance was 18% in Iran; it was 13. 2% in France and 39. 47% in Italy.
The average antibiotic resistance is higher in Iran than developed countries . According to the available statistics various antibiotic resistance tests are necessary for better treatment strategy selection.