Effect of Aerobic Training with Ginger Supplementation on some Liver Enzymes (AST,ALT,GGT) and Resistance to Insulin in Obese Women with Type 2 Diabetes

The levels of liver enzymes (AST, ALT, and GGT) are associated with obesity, fatty liver and insulin resistance, and nutrition and regular physical activities contribute to reducing these risk factors. The objective of this study is to assess the effect of ten-week endurance training with ginger supplementation on indicators of inflammation of the liver in women with type2 diabetes.
Material and In a randomized clinical trial study, 46 diabetes women aged 45 to 60 years (30≤BMI) divided into four groups randomly: exercise (E), exercise ginger (EPG), ginger (G) or placebo (P) groups. The blood samples were taken after 12 hours of overnight fasting at baseline and 48 hours after the last training session to measure levels of insulin, FBS and liver enzymes (AST, ALT and GGT). Then subjects of exercise group and exercise ginger group took part in ten-week aerobic training program for diabetic people.
At the end of week 10, in the EPG and E groups the levels of AST and ALT were significant reduced (P≤0.05). Besides, the weight, body fat percentage, WHR), levels of FBS and HOMA-ir was decreased only in the EPG and ET groups (P≤0.05). Of course these changes were slightly higher in group of EPG. While there wasn’t any significant changes in the control group (P>0.05).
The present study showed that aerobic exercises withusing ginger was more effective in significantly improving the liver enzymes levels, FBS, HOMA-ir and body composition compared with just aerobic exercise or ginger in obese women with type 2 diabetesý.