The effect of acute bout of aerobic activity with moderate intensities on CD34+ stem cells circulating numbers in middle-aged men

Background& The purpose of this study was to investigate the effect of acute bout of aerobic activity with moderate intensities on CD34 stem cells circulating numbers in middle-aged men.
24 middle aged men (Age 51.21 ± 3.51 yrs, Height 174.71 ± 5.67 cm and Weight 82.15 ± 8.94 kg) selected as the samples in this study and randomly divided into 3 groups (control group N: 8, experimental group A N: 8, experimental group B N:8). experimental groups (A:60% and B:70% VO2max) ran for 30 minutes on the treadmill. To measuring CD34 stem cells, befor and 10 minutes after the test protocol, blood samples were taken. To compare variation between and within the groups, we used One-Way analysis of variance test (ANOVA) and paired- samples T Test, respectively.
Both intensity of aerobic activity significantly increased the number of CD34 cells, in group A, this increase was 14% (P = 0.002), while this effect was higher in group B with 22% (P =0.003), but no significant difference was observed between the two groups and the control group no significant change from pre-test to post-test (P= 0.082). The relationship between changes in levels of CD34 cells with LDL/HDL and Chol/HDL ratios was not significant.
aerobic activity with intensities 60% and 70% of Vo2max can significantly increased the number of circulating CD34 cell in the peripheral blood and because of the potential role of these cells in neo-angiogenesis and vasculogenesis, they can possibly help repair and regeneration vessels.