The effect of ethanolic extract of Teucrium polium on Candida glabrata colonization in the liver, spleen and kidneys

Teucrium polium is a medicinal plant which species have been used for over 2000 years in traditional medicine. The aim of this study was evaluation of the effect of ethanolic extract of Teucrium polium on Candida glabrata colonization in mice tissue.
Material and The study was performed on 90 mature male mices (9 per group), that were devided into 10 groups: normal, placebo, 3 treatment group (candida- extract), control positive (Candida glabrata) and control negative (extract). Treatment groups were received 50,100 and 200 mg/kg dosages of extract for 20 days (every other day) by intraperitoneal injection. At the end of injections, homogenized liver, spleen and kidney were cultured on SDA medium and then colony count were performed.
The results showed, that liver in 100 mg/kg, spleen and kidney in 200mg/kg haven’t any yeast.
Discussion and According to the results, Teucrium polium extract, perhaps can stimulat the immunity against Candida glabrata.