Doping, Autologous blood transfusion,New biomarkers

Article Type:
Research/Original Article (بدون رتبه معتبر)
Abstract:
Background And Aim
Autologous blood transfusions (ABTs) increase the performance of athletes by increasing the oxygen carrying capacity and the number of red blood cells, and is the most challenging doping in diagnosis in recent years. The purpose of this study was to examine the methods and biomarkers that have been used to diagnose ABTs. with the keywords of autologous blood transfusion, autologous doping.
Material and
Methods
In this review article, articles were analyzed with the keywords of autologous blood transfusion, autologous doping. in the Pubmed database, google scholar.
Results
In the detection of blood doping, various methods and biomarkers have been introduced that can show nearly autologous blood transfusions, such as: capillary electrophoresis, iron, hepcidin, di (2-ethylhexyl) phthalate (DEHP), micro-RNA, Mass of total hemoglobin (tHb), and passport biological athlete (ABP).
Conclusions
unlike doping of homologous blood transfusion and erythropoietin stimuli, there is currently no direct way to determine doping through autologous blood transfusion. Receiving (injections) of blood currently examines individual hematological variables through the process of biological sports passport (ABP), and this requires more correction. Additional indirect biomarkers can increase the sensitivity and specificity of the method.
Language:
Persian
Published:
فصلنامه آزمایشگاه و تشخیص, Volume:10 Issue: 39, 2018
Pages:
9 to 14
magiran.com/p1838144  
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