Effects of Methamphetamine Toxicity on the Nervous System

Methamphetamine (METH) is a drug which is highly addictive, psychoactive and hallucinogenic. Besides marijuana, it is the second widely-used drug all over the world, especially by young people and adolescents. The wide use of METH has opened a new era in social problems. It has been proved that these compounds have toxic effects on the central nervous system. Regular use of METH can damage the dopaminergic and serotonergic synaptic network in different parts of the brain. Memory and learning disorders, anxiety and depression as well as motor disorders, such as Parkinson's disease, are among the toxic side-effects of the drug on the neuronal system. In addition, evidence suggests that this compound can cause schizophrenia, cognitive disturbances, and motor disorders in some consumers. In spite of the devastating effects caused by METH, the exact mechanism of action has not been understood yet, which has created a major challenge to the treatment strategies.
Today, using METH is highly increasing among the youth and teenagers. Sufficient knowledge and awareness on the catastrophic and irreversible side-effects of this drug can prevent serious harm to the public health.