Antibiofilm and Antibacterial Activity of Pistacia Atlantica against some Pathogenic Bacteria

Bacterial infections and the antibiotic resistance of pathogens are the most important challenges faced by researchers and physicians. In this study, the antibacterial and antibiofilm properties of methanol extracts of leaf, fruit, and gall of Pistacia atlantica were evaluated against some of pathogenic bacteria.
Leaf, fruit, and gall of Pistacia atlantica were collected from forests of Lorestan Province, Iran. Antibacterial properties were investigated against Staphylococcus aureus, Bacillus cereus, Enterococcus faecalis, Pseudomonas aeruginosa, and Escherichia coli through the well diffusion method. The microdilution method was used to determine the minimum inhibitory concentration and the minimum bactericidal concentration. The antibiofilm activity of methanol extract was studied in the sub-lethal concentrations on biofilm formation of Staphylococcus aureus and Pseudomonas aeruginosa using microtiter plate method.
Findings: The methanol extracts of leaf, fruit, and gall of Pistacia atlantica had significant antibacterial effects against the tested bacteria except Escherichia coli. There was a significant relationship between the antibacterial activity and the extract concentration (P The methanol extracts of different parts of Pistacia atlantica had antibacterial effects. In addition, the methanol extract reduced biofilm production of Staphylococcus aureus and Pseudomonas aeruginosa.