Effect of pesticide Glyophosate on histological lesions of kidney in common carp (Cyprinus carpio)

Abstract. Glyphosate is one of the most used pesticides in the agriculture. This study was aimed to evaluate the effect of pesticide glyphosate on histopathology of kidney in common carp (Cyprinus carpio). To this aim, glyphosate treatments were 0, 6, 7, and 8 mg of each treatment with three replications. 150 pieces of fish with an average weight of 30 ±5 were randomly divided in 12 of the 80 liter tank with 40 liters. At the end of the 70 days growing period for study of histopathological lesions of kidney, anesthetic of clove powder samples of kidney were performed. Histopathologic examination results showed that significant changes in kidney were performed. Renal tubular necrosis begins to accumulate of congestion; destruction and necrosis of tubular epithelial cells hemorrhage and congestion were observed in the urinary tract. In General, result confirmed that chronic concentrations of glyphosate had more physiologic effects like histopathological lesions on common carp like renal tubular necrosis, bleeding and renal tubular necrosis and urethral hypertension; these changes can be used as bio-indicator of glyphosate effects of this fish.