Survey of prevalence and determination of antibiotic susceptibility pattern of Klebsiella oxytoca strains isolated from inpatient and outpatient patients
Author(s):
Article Type:
Research/Original Article (دارای رتبه معتبر)
Abstract:
Background And Aims
Klebsiella oxytoca is an opportunistic pathogen which damages intestinal epithelium through producing cytotoxin. Cytotoxin is one of the important pathogenic factors, which plays a role in the virulence of this bacterium. The aim of this study was to survey of prevalence and determination of antibiotic susceptibility pattern of Klebsiella oxytoca strains isolated from inpatient and outpatient patients.Methods
In this analytical-descriptive study, a total of 75 isolates of K. oxytoca were isolated from various clinical samples (urine, stool, blood, wound and respiratory secretions), and after performing standard microbiological tests and using PCR method they were verified as K. oxytoca. Susceptibility testing of isolates was performed by disc diffusion method according to criteria recommended by the Clinical and Laboratory Standards Institute (CLSI).Results
Of all the 75 isolates, seven K. oxytoca strains isolated from the stool cultures, eleven strains isolated from the blood cultures, two strains isolated from the wound cultures, and fifty-one strains isolated from the urine cultures and four K. oxytoca strains isolated from the respiratory secretions. Antibiotic susceptibility test results showed the highest and lowest resistance was related to ticarcillin (81.3%), meropenem and imipenem (1.3%) respectively. A multi-drug resistant strain was isolated from the urine of a hospitalized woman.Conclusion
In Conclusion, the results of this study showed that the isolation and identification of K. oxytoca strains is important and determination of the antibiotic susceptibility pattern of these isolates is necessary in order to prevent the increase of antibiotic resistance and the emergence of multi drug resistance strains of K. oxytoca.Keywords:
Language:
Persian
Published:
Journal of Shahrekord University of Medical Sciences, Volume:20 Issue: 4, 2018
Pages:
76 to 86
magiran.com/p1879680
دانلود و مطالعه متن این مقاله با یکی از روشهای زیر امکان پذیر است:
اشتراک شخصی
با عضویت و پرداخت آنلاین حق اشتراک یکساله به مبلغ 1,390,000ريال میتوانید 70 عنوان مطلب دانلود کنید!
اشتراک سازمانی
به کتابخانه دانشگاه یا محل کار خود پیشنهاد کنید تا اشتراک سازمانی این پایگاه را برای دسترسی نامحدود همه کاربران به متن مطالب تهیه نمایند!
توجه!
- حق عضویت دریافتی صرف حمایت از نشریات عضو و نگهداری، تکمیل و توسعه مگیران میشود.
- پرداخت حق اشتراک و دانلود مقالات اجازه بازنشر آن در سایر رسانههای چاپی و دیجیتال را به کاربر نمیدهد.
In order to view content subscription is required
Personal subscription
Subscribe magiran.com for 70 € euros via PayPal and download 70 articles during a year.
Organization subscription
Please contact us to subscribe your university or library for unlimited access!